Protein Alignment drpr and scarf1

DIOPT Version :10

• Sequence 1: NP_001261276.1
• Gene: drpr / 38218
• FlyBaseID: FBgn0027594
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: XP_001344375.3
• Gene: scarf1 / 100005273
• ZFINID: ZDB-GENE-030131-8778
• Length: 888
• Species: Danio rerio
• Alignment Length: 1019
• Identity: 231/1019 - (22%)
• Similarity: 315/1019 - (30%)
• Gaps: 442/1019 - (43%)

  Fly    84 VRD----CCDGYIASAGEC-VPHCSEPCQHGRCISPEKCKCDHGYGGPACDINCPPGWYGRNCSM 143
            |||    ||.|:..|..|| ||.|.                                  |...
Zfish    33 VRDSSAICCSGWGQSGDECTVPLCE----------------------------------GERA-- 61

  Fly   144 QCDCLNNAVCEPFSGDCECAKGYTGARCADICPEGFFGANCSEKCRCENGGKCHHVSGECQCAPG 208
               ||.:.|| .:.|.|.|..|:.|.:|...||..|:|.:|.|.|.|...|.|...:|.|.|.|
Zfish    62 ---CLQDEVC-VYPGLCRCKAGFYGYQCKAPCPPEFWGPDCREFCPCHPHGLCDPATGVCSCLP- 121

  Fly   209 FTGPLCDMRCPDGKHGAQCQQDCPCQNDGKCQPETGACMCNPGWTGDVCANKCPVGSYGPGCQES 273
                        .:.|:.||..|.|...|||.|..|.|.|..||....|:..|
Zfish   122 ------------NRWGSLCQNSCKCGRHGKCDPVYGNCTCEEGWWTSTCSKAC------------ 162

  Fly   274 CECYKGAPCHHITGQCECPPGYRGERCFDECQLNTYGFNCSMTCDCANDAMCDRANGTCICNPGW 338
                                         :|.|.|              :.||:|.|.||||.|:
Zfish   163 -----------------------------QCHLAT--------------STCDQATGRCICNEGY 184

  Fly   339 TGAKCAERICEANKYGLDCNRTCECDMEHTDLCHPETGNCQCSIGWSSAQCTRPCTFLRYGPNCE 403
            .|.||:          |.||    |   :...|...||.|||..||             :||:|:
Zfish   185 WGQKCS----------LPCN----C---YVSPCQQRTGTCQCLHGW-------------WGPSCD 219

  Fly   404 LTCNCK-NGAKCSPVNGTCLCAPGWRGPTCEESCEPGTFGQDCALRCD-CQNGAKCEPETGQCLC 466
            ..|.|. |.|.|....|.|||.||::.|.|.|.|:.|.:|:.|...|. |:.|..|.
Zfish   220 RRCICNLNNADCDVQTGGCLCYPGYKEPFCNEPCDSGKYGRGCKNSCGRCEGGRPCS-------- 276

  Fly   467 TAGWKNIKCDRPCDLNHFGQDCAKVCDCHNNAACNPQNGSCTCAAGWTGERCERKCDTGKFGHDC 531
                   |.|..||                  ||.|         ||.|.||:::|.
Zfish   277 -------KLDGLCD------------------ACEP---------GWNGTRCDQRCP-------- 299

  Fly   532 AQKCQCDFNNSLACDATNGRCVCKQDWGGVHCETNCRSGYYGENCDKVC-RCLNNSSCDPDSGNC 595
                                                 :||||..|.::| .|.|...|||::|.|
Zfish   300 -------------------------------------AGYYGHRCQEICPHCRNMDPCDPETGAC 327

  Fly   596 I-CSAGWTGADCAEPCPPGFYGMECKERCPEILHGNKSCDHITGEILCRTGYIGLTCEHPCPAGL 659
            : |:.||||..|.:||..|.||..|:..|       |:|:|
Zfish   328 LQCNPGWTGPRCDKPCTDGRYGDGCRFLC-------KTCNH------------------------ 361

  Fly   660 YGPGCKLKCNCEHGGECNHVTGQCQCLPGWTGSNCNESCPTDTYGQGCAQRCRCVHHKVCRKADG 724
                          |.|:||||:|.||||:.|.:||.:||.:.||..|:..|.| ..:.|..|.|
Zfish   362 --------------GHCDHVTGRCICLPGFQGESCNSTCPFNLYGFNCSSTCDC-GSQACHPATG 411

  Fly   725 MCICETGWSGTRCDEVCPEGFYGEHCMNTCACPSANFQCHAAHGCVCRSGYTGDNCDELIASQRI 789
                                          |||
Zfish   412 ------------------------------ACP-------------------------------- 414

  Fly   790 ADQSENSSRASV-------ALTLVLMTLFACIIFAVFIYYRRRVSNLKTEIAHVHYTHDTNPPSW 847
                 |||||.:       ...|:|..||.|......:..:.||:           ..|.:|...
Zfish   415 -----NSSRAGLLAGLLIPLCILILALLFCCCCCGRPVEGKERVT-----------VGDGSPAVR 463

  Fly   848 PPNHNFDNPVYGMQAETRLLPNNMRSKMNNFDQRST----MSTDYGDDCNASGRVGSYSINYNHD 908
            ..:|     ||.:.|       ||.|.|......|:    ::..:.|.          .:.:||.
Zfish   464 MKHH-----VYTVLA-------NMGSAMPCITLWSSGLPRVTVSHHDP----------ELTFNHS 506

  Fly   909 LLTK--------NLNADRTNPIVYNESLKEEHVYD------EIKHK-EGYKDPVKIYSKILFPED 958
            .:.:        :...|.....||.|..:|:.:.:      |:..| ..:.||....|     ||
Zfish   507 FIEQPSSGWVIDSFETDEDGEAVYCEPPREDVLTEAGGELQELNSKCNFFPDPSTFSS-----ED 566

  Fly   959 EYDHLDYSRPSTSQKPHYHRMNDAMLNINQDEEKPSNVKNMTVLLNKPLP--------------- 1008
            ........|.|:..|.....::.|.......:|:.|:.:::.....||.|
Zfish   567 MSQAFGIPRTSSIAKSKRPSVSFAEGTKFSPKERRSSTQDLQGTARKPKPWGVLMISALQGGQGN 631

  Fly  1009 ---PTEPEPQHECFDNTNTNLDNVSTASP----------SSSPK 1039
               .||.|.:.:   |...|:.....||.          ||.|:
Zfish   632 QNNETETEKEEK---NDEENISEEQRASSETLQNDSERYSSGPQ 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drpr	NP_001261276.1	EMI	26..92	CDD:462204	6/11 (55%)
		EGF_CA	274..319	CDD:473889	3/44 (7%)
		gliding_CglD	<451..579	CDD:468178	21/127 (17%)
		DSL	567..609	CDD:473190	19/43 (44%)
scarf1	XP_001344375.3	EGF_CA	361..401	CDD:473889	21/77 (27%)