Protein Alignment RabX5 and RAB6C

DIOPT Version :10

• Sequence 1: NP_647644.2
• Gene: RabX5 / 38209
• FlyBaseID: FBgn0035255
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_115520.2
• Gene: RAB6C / 84084
• HGNCID: 16525
• Length: 254
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 73/244 - (29%)
• Similarity: 118/244 - (48%)
• Gaps: 42/244 - (17%)

  Fly    40 LSKERDFGAQVRYYLEAPRKPKFRPCKVIFVGDCSVGKTAIVNRFCYDKFQSNYKATIGVDFELE 104
            :|...|||..:|         ||   |::|:|:.||.||:::.||.||.|.:.|:|.||:||..:
Human     1 MSAGGDFGNPLR---------KF---KLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSK 53

  Fly   105 NFSILGHNYSLEMWDTAGQERFRCIAGAYYRNASVIVVTYDMSKKDSLESAKKWLNSALNYNASK 169
            ...:......|.:||||||||.|.:...|.|:::..||.||::..:|.:...||::.......|.
Human    54 TMYLEDGTIGLRLWDTAGQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSD 118

  Fly   170 RPLVFLVGTKADLLSKEEFVRMERLAGLAAAELQAEYWSVSARSGFKVTELFQRIAAL-----AF 229
             .::.|||.:.||..|.: |.:|. ....|..|...:....|::|:.|.:||:|:||.     :.
Human   119 -VIITLVGNRTDLADKRQ-VSVEE-GERKAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMEST 180

  Fly   230 EEAVMQEIRSIK-NKPQEQATQASVKSQTFDLRNFFGSRLSQQKSGCTC 277
            ::...:::..|| .|||||..                     .:.||:|
Human   181 QDGSREDMSDIKLEKPQEQTV---------------------SEGGCSC 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX5	NP_647644.2	P-loop containing Nucleoside Triphosphate Hydrolases	66..230	CDD:476819	56/168 (33%)
RAB6C	NP_115520.2	Required for centrosome localization	1..174		63/187 (34%)
		Rab6	14..174	CDD:206654	57/165 (35%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20340	32..50		9/17 (53%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20340	69..88		9/18 (50%)