DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7974 and zgc:103692

DIOPT Version :9

Sequence 1:	NP_001261273.1	Gene:	CG7974 / 38207	FlyBaseID:	FBgn0035254	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001005945.1	Gene:	zgc:103692 / 449772	ZFINID:	ZDB-GENE-041010-15	Length:	289	Species:	Danio rerio

Alignment Length:	292	Identity:	151/292 - (51%)
Similarity:	194/292 - (66%)	Gaps:	27/292 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 KNLRQRK--NSDEEEKEEQLT----LDEIKERQRLRQRPNGVSLVGLALGKKIAPEEELAIKDPF 81
            ||.|:||  :||||:.|.:..    |||.||.|.||:|.:|||:..|.:|:|:..|.||. .|||
Zfish     5 KNFRRRKEDSSDEEDDETKFVVRSKLDEAKELQSLRKRQHGVSIATLLVGEKLPLEAELE-DDPF 68

  Fly    82 NVKTGGLVNMKQLKSGKMKEADDAYDVGIGTQFSAETNKRDEDEEMMKYIEQELQKRKGGGTEDA 146
            .:||||:|:||::|........|..|:.:||.||||||:||||.:||||||.||:|:||     .
Zfish    69 KLKTGGVVDMKKVKDRSRDMTVDENDLNLGTSFSAETNRRDEDADMMKYIETELKKKKG-----M 128

  Fly   147 AEDDGDVNKYLTPEDAALYALPDHLRQSSSHRSEEMLSNQMLNGIPEVDLGIVAKIRNIEATEEA 211
            .|.:....|...||| .||.||:::..||:.::|||||||||:|||||||||.|||:||..||||
Zfish   129 VEAEEQKVKVKNPED-LLYELPENINVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIINTEEA 192

  Fly   212 KQKLLQDAKN-KKDGPSQFVPTNMAVNFMQHNRFNIEDNSDQRRRKREE------REGN--KSAQ 267
            |.|||.:.:| |||..:.|||||:|||::|||||..||::..:||.|||      |.|:  |.|.
Zfish   193 KAKLLAEQRNKKKDSGTSFVPTNIAVNYVQHNRFYHEDSNAPQRRNREEPKARPLRVGDTEKPAP 257

  Fly   268 HQTNPNGVKR-----ATDDYHYDKFRKQFRRY 294
            ..:.||..||     |||||||:||:|..|||
Zfish   258 EASPPNFRKRPNNEKATDDYHYEKFKKMNRRY 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7974	NP_001261273.1	Hep_59	113..214	CDD:284467	60/100 (60%)
zgc:103692	NP_001005945.1	Hep_59	100..195	CDD:284467	60/100 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582198
Domainoid	1	1.000	111	1.000	Domainoid score	I6226
eggNOG	1	0.900	-	-		E1_KOG3345
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9551
Inparanoid	1	1.050	249	1.000	Inparanoid score	I3229
OMA	1	1.010	-	-		QHG59632
OrthoDB	1	1.010	-	-		D1493869at2759
OrthoFinder	1	1.000	-	-		FOG0006447
OrthoInspector	1	1.000	-	-		oto39969
orthoMCL	1	0.900	-	-		OOG6_103943
Panther	1	1.100	-	-	LDO	PTHR13486
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4416
SonicParanoid	1	1.000	-	-		X5410
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800