Protein Alignment Srrm234 and Srrm234

DIOPT Version :10

• Sequence 1: NP_001097475.2
• Gene: Srrm234 / 38206
• FlyBaseID: FBgn0035253
• Length: 1655
• Species: Drosophila melanogaster
• Sequence 2: XP_061498500.1
• Gene: Srrm234 / 1276710
• VectorBaseID: AGAMI1_012372
• Length: 1736
• Species: Anopheles gambiae
• Alignment Length: 1771
• Identity: 463/1771 - (26%)
• Similarity: 684/1771 - (38%)
• Gaps: 627/1771 - (35%)

  Fly   164 GHAITTTTTEKSAAISTP--GSKTSSPRTQTGEPASSAPSATSNGARKTKAPYFQHDNREYLA-- 224
            |||  |...|:....|.|  |......|........|..||..: ||.:      |.:..:|.
Mosquito   262 GHA--TFHPERRDVCSRPTTGGSVRIARQPKANQKDSVQSAAGH-ARSS------HRHNRHLGDV 317

  Fly   225 -KYESFRLTAHTWNYAAVARKFKPLRPALASGANKTRRPAVSKRTHPDCAC------ACQ----- 277
             ...|::..||..::                     |.|..|..:....:|      :||
Mosquito   318 LSRSSYQRQAHHHHH---------------------RHPQDSGSSSRSSSCDSSEVVSCQVRKLY 361

  Fly   278 --------QKDPEP-------------ALEPAHR--TAEH--SIQKEL-----------PSSQMK 306
                    |.:.||             .|||.|.  ..||  |:|..|           |..::.
Mosquito   362 HHHHHHHHQDEAEPNVRRQTGCPNRHQYLEPQHAQLVREHCGSLQPHLHPHNRHHHPSAPHQKLC 426

  Fly   307 INIDGSVLLELLKYSSSSLLGTLLGAGSAVATSARDTHQIAEAQQQKNARLREAFNISEYFVEGS 371
            |....:........:.::.:...:.|..:| .|.|:||.||:|||:|||:|||||.||:|||||:
Mosquito   427 IRTTTAAASRSSAAAPAASVPFCMHAMHSV-VSVRETHHIAQAQQEKNAKLREAFGISQYFVEGT 490

  Fly   372 SFDGDRKAKEDLAKSVALQKELDAQRESLAAAAAAAAAGKDKETG--KRYALVRTPSRERDRDAG 434
            |||.|||||||||||.|||||| |::|.          .|:.|..  ||||||||||.|::...|
Mosquito   491 SFDQDRKAKEDLAKSEALQKEL-AEKEK----------AKEMELANRKRYALVRTPSPEKEAGGG 544

  Fly   435 DAAA---NG---------DERD----------------------------------HVSKTDKKK 453
            ....   ||         |||:                                  ...|.:|||
Mosquito   545 GTGGSDRNGKQRRRGSSNDEREEGEHDDDDEEENDGSHEGGDGKVNNSKSTAGGGLRRDKEEKKK 609

  Fly   454 RKKRARESSASPERK--KKKKSKKHKKESKSKKKRSRK--RKHSESGRDSDRDSDEEDDSSEEER 514
            :||:||:.|:|||||  |||||||:||| ::|||.|:|  |.......||:.|||.:.|:|.:..
Mosquito   610 KKKKARDVSSSPERKKDKKKKSKKNKKE-RTKKKHSKKSHRDDESDSSDSESDSDSKSDASSDSE 673

  Fly   515 RE----SKNVRKKAKKDKKKRDKKLKKKSRARASSSDSERTNSPSRKENKSDRSRGAKASKSDEK 575
            ||    ||..:|.:||:|||:.:| |||:::|          ||||  |||..:.|.|.:..:.|
Mosquito   674 RENNSSSKRKKKSSKKEKKKKSQK-KKKAKSR----------SPSR--NKSPDASGKKVAVEEPK 725

  Fly   576 APQQENVM-----------------------RSRSRERKDTRSSRPLEASIDSRQRKPRERSAA- 616
            ..::..|.                       ||.||.|.|.:.:|.     .||:|....|...
Mosquito   726 QDKRHEVSAGAKHDTDRNRRSHDRSAGGRRDRSSSRNRSDVQRTRE-----SSRERGNNARRGGG 785

  Fly   617 --TPPRKEP-------------ERHRERSKDR--QRSKEKHRSRDRLRSRERQRSRERQRSRERQ 664
              ....:||             .|||:|.:||  .|:.|:...|:|.|:|.|:||...|...:|.
Mosquito   786 YRADRYEEPRFGNNNRGGGDYFNRHRDRDRDRDSNRAAEERPRRNRSRNRRRERSPPDQERNDRS 850

  Fly   665 RSKERQRSKERQRSIER-------QRSKERQRSKERQRSRSKDALRCKEKPQCNEKERSRERRRS 722
            ||:.|.||..::|.::|       :|||:   |..|:|:.:|         |..|.||:|:|...
Mosquito   851 RSRSRSRSGSQRRRLDRGARGHSVERSKQ---SSRRERTPTK---------QQAEHERARDRDGD 903

  Fly   723 KSKD-RQRSKEKHRPKDEQQSVDKRRDRSTDRSKENQRSNERQRSKERQRSKERERSKDRQRSRE 786
            :.|| |:|:|.:.|.:.:.|.:|::|||..:|     |:::|.|.:|.:|.:||:.::|..:.|.
Mosquito   904 REKDRRERNKGRDRDEHDHQQLDRQRDRDRER-----RNDDRDRGREGKRDRERDSNRDPAKHRR 963

  Fly   787 ----RRRSKEGQLSKDRQGLKERQRSNERKRSKERQPSKEKQR------SRERQRS-REPLQSKD 840
                :::.|....:..||..:|...:.:|.:|..|.|.::|.:      |:..:|| ..|.::..
Mosquito   964 SPSPQKKDKRSPATARRQPREEESTAKKRDKSPRRSPDRQKSKLSTGVESKALKRSPTPPPKAAS 1028

  Fly   841 RQRSKERQRSR-ERPAKEARPT----------------------------RSPR------ERSSK 870
            |.:|..|...: ||||...:|.                            |:|.      :||||
Mosquito  1029 RDKSIPRGSDKVERPASSRQPAPAKVAEEKEPASSSDSEAESELDYSPARRNPERYSDILQRSSK 1093

  Fly   871 SRDDRRHRSPTNASRKQKDDTKLSRNARFKSPAHSPEAPPKKSVPTPAFNPFKAAEDTVNDILGT 935
            ||.:      ||.....:..||.::..  .|.:.||..|.:.|.|
Mosquito  1094 SRTE------TNGKEDDRKSTKTTKPV--SSRSGSPREPRRSSSP-------------------- 1130

  Fly   936 KSVMVALEQTKRQRAASSSSSDSDSSGSSSTSSRTPSPKP------TPRKQKKRSKTPELKEVKK 994
                       |...|.|.::..||:..:..:|.:|||.|      ..|.:.:||.:|:    |:
Mosquito  1131 -----------RGEKADSKTAKKDSAPKARRASVSPSPPPARRDRSASRTKSRRSPSPK----KR 1180

  Fly   995 EISPRKESRVSVKREQSNSP--QKSKSKSKVDESSPKRTSRRSRSISSELR-----YSPAER--- 1049
            :.|..:.|.|:.|||:..:|  :|.:.:|....||.:|...||||.....|     .|||.|
Mosquito  1181 DTSRHEASPVAKKREKPVAPPAEKPEKRSTTSPSSTRRVKSRSRSPPEVKRRRQEQASPAARSTT 1245

  Fly  1050 HPERYHDIVQDKKR-------PSKVREAHSTKPA---------------------PVVRLRAQSD 1086
            .|....:..:..||       .|:.|::.|.|.:                     |||:|.:...
Mosquito  1246 KPTSERESTETAKRSETRTPEKSESRKSRSKKASSSSGGAAAASSSSTNAAPVQQPVVKLHSPES 1310

  Fly  1087 DGSDAETGVDGAALEEFQQSR------------------REREEQQELRMLEQLKSGIAAKAKQK 1133
            :.|.:    ||   ||.||.|                  ..||::::|.:|:.||..:||||||.
Mosquito  1311 EHSQS----DG---EERQQERSSTLRDRDDLDAFLPIYDETREQEKDLSLLKALKHDLAAKAKQS 1368

  Fly  1134 IKIMEKDPAKEGSEVSGSDQVTATKRNSLSEFLVANNVTALINTLTTTTVTLTTTPPPPLAVVVP 1198
            ::                      |:.|:||  |.|   :.|::..::.:.:.....||   ..|
Mosquito  1369 LE----------------------KKKSVSE--VGN---SSISSSISSAIAMKVGVLPP---TKP 1403

  Fly  1199 LEQRQEQPQQRDPDRELSVPVEDTVKKRDTSTPPICKTPQVTANGDAKSPTLVHKNHVHHNRPPP 1263
            .|....:.::||..:..:.| ..:.|....|...:.    |..:.|.|.|.
Mosquito  1404 GEPASAEARERDLQQSATQP-SSSHKSESASKAALA----VKCSPDEKLPA-------------- 1449

  Fly  1264 QHMHHHSQQQQHHQHPPGKRIFHNRTLNNNPNSRHSTNNPHACGGGGVPHSNSNSSNSGGNNNNA 1328
                                       ...||:..:| :|.|        |..::|::.
Mosquito  1450 ---------------------------GAKPNTTKAT-DPAA--------SQEDTSSTS------ 1472

  Fly  1329 AMLPFLAGTPGTYNRTTNRLNHGPLLTATHYNICKNHQHSLQQQQAHHLARGLVYNSALFGHGQR 1393
                                      ||...:|   |:
Mosquito  1473 --------------------------TALKKDI---HE--------------------------- 1481

  Fly  1394 HPGLLSLTGAGVGMSGPGAPLLGHPSHVRGGGGPISFNAAAAAAAVAANSISYLHHHHQHQQKPK 1458
               :|:..||.....|                       :.|||::|..:|  ||
Mosquito  1482 ---ILTTVGAWAVADG-----------------------SEAAASLAKTTI--LH---------- 1508

  Fly  1459 IVIKPFKIHDPQPLVAALADSSLVDAIVSKVSTAT------VAAAESAARRSRSRERRSRSKRRT 1517
                                  .||.|:.:..:.|      .|.|.|.:.::|...:.|||:.|:
Mosquito  1509 ----------------------AVDGILKEKISGTSKEAKPAAVAGSGSNKTRPSTKSSRSRSRS 1551

  Fly  1518 STSHHRHDSSSESRSRYSSSSSRSGSHSSRSGSHSSRTSCSTNSSSGSSS-SGSGSGSSQSGSRS 1581
            .:..|:..|.|.|.|  .|.||||.||||.|.||||....|:.|.|.||| |...|..|::.|||
Mosquito  1552 RSRSHKSRSYSSSSS--DSGSSRSRSHSSSSHSHSSSDRGSSRSRSRSSSHSSQSSPRSRTASRS 1614

  Fly  1582 PSIPRRRGSPSFLDRRRIT--------SARKRPIPYHHKANAEGEVEDASSCCSSCFSRASSPAT 1638
            ||||||.||||||||||||        |.|.||.......::......:|...:|...|.||
Mosquito  1615 PSIPRRAGSPSFLDRRRITRSSRSPPRSFRSRPDVRRRGRHSSKSPRSSSDASASSHRRHSS--- 1676

  Fly  1639 PLLTPLRNSRSPSMAA 1654
                   .|||.|.:|
Mosquito  1677 -------RSRSRSRSA 1685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srrm234	NP_001097475.2	cwf21_SRRM2-like	52..100	CDD:410600
		PTZ00121	<560..1154	CDD:173412	183/750 (24%)
		U2AF_lg	747..>876	CDD:273727	42/174 (24%)
		SRRM_C	<1584..1612	CDD:464573	20/35 (57%)
Srrm234	XP_061498500.1	None