DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vta1 and FKS1

DIOPT Version :9

Sequence 1:	NP_647640.1	Gene:	Vta1 / 38204	FlyBaseID:	FBgn0035251	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_013446.1	Gene:	FKS1 / 851055	SGDID:	S000004334	Length:	1876	Species:	Saccharomyces cerevisiae

Alignment Length:	285	Identity:	53/285 - (18%)
Similarity:	87/285 - (30%)	Gaps:	105/285 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 TRDVVIAYWARLYALQVGLKASTQTGEETKLLLGIMDWLEQMKKQYAENEAITNEVAAQAHIENY 89
            |.|:.|.|..::...||                    |...:...|.|:      :.|..|::.
Yeast   737 TTDMEIKYKPKVLISQV--------------------WNAIIISMYREH------LLAIDHVQK- 774

  Fly    90 ALKLFLYADKQDREENFGKNVVKA--FYSSGVLYDILQTFGELSEEALHNRKYAKWKAAYIHNCL 152
                .||  .|...|..||..::|  |:.|       |.......|.......|:.:.::....|
Yeast   775 ----LLY--HQVPSEIEGKRTLRAPTFFVS-------QDDNNFETEFFPRDSEAERRISFFAQSL 826

  Fly   153 KNGETPIPGPLPDDDDEAELEGENANASADTSPEDAAGAAAPAPYQPEPDSQPPAPSSPTTSGVV 217
               .||||.|||.|                                          :.||.:.:.
Yeast   827 ---STPIPEPLPVD------------------------------------------NMPTFTVLT 846

  Fly   218 PPTAEEVLNNPNKLPSPPVDEEKPGGFVPYVPTAQPNPATAATIYQPIVPVAGVQITPDQMITAQ 282
            |..||.:|.:..::    :.|:.           |.:..|.....:.:.||.......|..|.|:
Yeast   847 PHYAERILLSLREI----IREDD-----------QFSRVTLLEYLKQLHPVEWECFVKDTKILAE 896

  Fly   283 KYCKYAGS---ALNYDDVKTAIENL 304
            :...|.|:   |...|.:|:.|::|
Yeast   897 ETAAYEGNENEAEKEDALKSQIDDL 921

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vta1	NP_647640.1	Vta1	18..148	CDD:398366	23/124 (19%)
Vta1	NP_647640.1	Vta1_C	275..311	CDD:407932	10/33 (30%)
FKS1	NP_013446.1	RCR	<18..80	CDD:403477
		FKS1_dom1	300..409	CDD:405046
		Glucan_synthase	808..1631	CDD:396784	31/174 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342031
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930