DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vta1 and vta1

DIOPT Version :9

Sequence 1:	NP_647640.1	Gene:	Vta1 / 38204	FlyBaseID:	FBgn0035251	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	XP_005160712.1	Gene:	vta1 / 406414	ZFINID:	ZDB-GENE-040426-2154	Length:	303	Species:	Danio rerio

Alignment Length:	320	Identity:	159/320 - (49%)
Similarity:	210/320 - (65%)	Gaps:	30/320 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PPSLKSIQHFLKLAQEHDTRDVVIAYWARLYALQVGLKASTQTGEETKLLLGIMDWLEQMKKQYA 71
            ||.||:|||:|:.||||:.||.|:||:.||||:|.|:|..::|.|..|.|:.:||.||.|||:..
Zfish     4 PPQLKAIQHYLRTAQEHEKRDPVVAYYCRLYAMQTGMKLDSKTPECRKFLVKLMDQLEMMKKELG 68

  Fly    72 ENEAITNEVAAQAHIENYALKLFLYADKQDREENFGKNVVKAFYSSGVLYDILQTFGELSEEALH 136
            :||:|:.|:...|||||||||:|||||.:||.|.|.||::|:||:|.:|:|:|..|||||||.|.
Zfish    69 DNESISQEIVGNAHIENYALKMFLYADNEDRSERFHKNMIKSFYTSSLLFDVLSVFGELSEENLQ 133

  Fly   137 NRKYAKWKAAYIHNCLKNGETPIPGPLPDD----DDEAELEGENANASADTSPEDAAGAAAPAPY 197
            .|||||||||||||||||||||.|||:..:    |||...||...:.:.|..|.     :.|: :
Zfish   134 QRKYAKWKAAYIHNCLKNGETPQPGPIGMEGEAYDDEFGAEGGGPSQAPDNPPH-----SQPS-F 192

  Fly   198 QPEPDSQPPAPSSPTTSGVVPPTAEEVLNNPNKLPSP----PVDEEKPGGFVPYVPTAQP--NPA 256
            :..|..||  |:|..::..:||.:....|.|.::|.|    ||   ||   || ||...|  :|:
Zfish   193 RGHPSDQP--PTSNFSNIQIPPGSHAPANTPAEIPHPEAAQPV---KP---VP-VPRTMPVVDPS 248

  Fly   257 TAATIYQPIVPVAGVQITPDQMITAQKYCKYAGSALNYDDVKTAIENLQKALKLLSTGSE 316
            ......:     ..|::||:....||||||||||||.|:||.||::|||||||||:||.|
Zfish   249 LLNNTQE-----GDVRLTPEDFTRAQKYCKYAGSALQYEDVGTAVQNLQKALKLLTTGKE 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vta1	NP_647640.1	Vta1	18..148	CDD:398366	75/129 (58%)
Vta1	NP_647640.1	Vta1_C	275..311	CDD:407932	25/35 (71%)
vta1	XP_005160712.1	Vta1	15..145	CDD:282502	75/129 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594151
Domainoid	1	1.000	192	1.000	Domainoid score	I3166
eggNOG	1	0.900	-	-		E1_KOG0917
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6473
Inparanoid	1	1.050	293	1.000	Inparanoid score	I2760
OMA	1	1.010	-	-		QHG56589
OrthoDB	1	1.010	-	-		D1450538at2759
OrthoFinder	1	1.000	-	-		FOG0006035
OrthoInspector	1	1.000	-	-		oto39757
orthoMCL	1	0.900	-	-		OOG6_102826
Panther	1	1.100	-	-	LDO	PTHR46009
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4945
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770