DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vta1 and Vta1

DIOPT Version :9

Sequence 1:	NP_647640.1	Gene:	Vta1 / 38204	FlyBaseID:	FBgn0035251	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	XP_006227708.1	Gene:	Vta1 / 292640	RGDID:	1305031	Length:	309	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	151/338 - (44%)
Similarity:	203/338 - (60%)	Gaps:	61/338 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PPCPPSLKSIQHFLKLAQEHDTRDVVIAYWARLYALQVGLKASTQTGEETKLLLGIMDWLEQMKK 68
            ||.|...|||||.|:.|||||.||.|:||:.||||:|.|:|..::|.|..|.|..:||.||.:||
  Rat     8 PPLPAQFKSIQHHLRTAQEHDKRDPVVAYYCRLYAMQTGMKIDSKTPECRKFLSKLMDQLEALKK 72

  Fly    69 QYAENEAITNEVAAQAHIENYALKLFLYADKQDREENFGKNVVKAFYSSGVLYDILQTFGELSEE 133
            |..:|||:|.|:...||:||||||:|||||.:||...|.||::|:||::.:|.|::..||||::|
  Rat    73 QLGDNEAVTQEIVGCAHLENYALKMFLYADNEDRAGRFHKNMIKSFYTASLLIDVITVFGELTDE 137

  Fly   134 ALHNRKYAKWKAAYIHNCLKNGETPIPGPLP-DDDDEAELEGENANASADTSPEDAAGAAAPAPY 197
            .:.:||||:|||.||||||||||||..||:. ::|::.|   ||.:..|.:.|
  Rat   138 NVKHRKYARWKATYIHNCLKNGETPQAGPVGIEEDNDVE---ENEDVGATSLP------------ 187

  Fly   198 QPEPDSQPPAPSSPTT-----------SGV-VPPTAEEVLNNPNKL------------PSPPVDE 238
                 :|||.|||.:|           ||: :||.|....|.|.::            |||..
  Rat   188 -----TQPPQPSSSSTYDPSNLAAGSYSGIQIPPGAHAPANTPAEVPHSTGVTSNAVQPSPQT-- 245

  Fly   239 EKPGGFVPYVPTAQPNPATAATIYQPIVPVAGVQITPDQMITAQKYCKYAGSALNYDDVKTAIEN 303
                  ||.:|...|:..||:.        ..|::||:....||||||||||||.|:||.||::|
  Rat   246 ------VPAIPAIDPDLYTASQ--------GDVRLTPEDFARAQKYCKYAGSALQYEDVSTAVQN 296

  Fly   304 LQKALKLLSTGSE 316
            |||||:||:||.|
  Rat   297 LQKALRLLTTGRE 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vta1	NP_647640.1	Vta1	18..148	CDD:398366	68/129 (53%)
Vta1	NP_647640.1	Vta1_C	275..311	CDD:407932	24/35 (69%)
Vta1	XP_006227708.1	Vta1	22..152	CDD:282502	68/129 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352226
Domainoid	1	1.000	179	1.000	Domainoid score	I3448
eggNOG	1	0.900	-	-		E1_KOG0917
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6473
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2906
OMA	1	1.010	-	-		QHG56589
OrthoDB	1	1.010	-	-		D1450538at2759
OrthoFinder	1	1.000	-	-		FOG0006035
OrthoInspector	1	1.000	-	-		oto96691
orthoMCL	1	0.900	-	-		OOG6_102826
Panther	1	1.100	-	-	LDO	PTHR46009
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4945
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810