Protein Alignment Tmep and HFL1

DIOPT Version :10

• Sequence 1: NP_001097474.1
• Gene: Tmep / 38185
• FlyBaseID: FBgn0035236
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_012977.3
• Gene: HFL1 / 853925
• SGDID: S000001759
• Length: 418
• Species: Saccharomyces cerevisiae
• Alignment Length: 406
• Identity: 114/406 - (28%)
• Similarity: 165/406 - (40%)
• Gaps: 100/406 - (24%)

  Fly    73 CVWAALFITCQQIY---QHLRWYTNPQEQRWIVRILFIVPIYATYSWISLLFFNSDNVYIYFFTV 134
            ||::::..|....|   :||..|..|.|||..:|||.:|||::......::  ..:....|...:
Yeast    14 CVYSSIIATIISFYTITRHLLNYRKPYEQRLSIRILLLVPIFSVSCASGII--KPEAAQFYVDPI 76

  Fly   135 RDCYEAFVIYNFLSLCYEYLGGEGNIMSEI------RGKPIKTSCLYGTCCLKGKTYTIG----F 189
            |:.|||||||.|.:.....||||.||::.:      ...||.   |.|..|   |...:.    |
Yeast    77 REFYEAFVIYTFFTFLTLLLGGERNIITVLSLNHAPTRHPIP---LIGKIC---KPIDLSDPFDF 135

  Fly   190 LRFCKQATLQFCLVKPLVAFIIIFLQAFGHYHDGDWSADGGYIYITIIYNISVSLALYGLYLFYF 254
            | |.|:..||:...||...|..:...|        |......|::.:.|||||:.:||.|.||:.
Yeast   136 L-FVKKGILQYVWFKPFYCFGTLICSA--------WKLPKFEIFLNVFYNISVTWSLYSLALFWK 191

  Fly   255 ATRDLLTPFEPVLKFCTIKSVIFLSFWQGV---GLAILEKANVISPIVDSAGTVTVEPGTVSAGY 316
            .....|||::|.|||..:|.:||.|:||.:   ||.:..|.        ..|......|.|   |
Yeast   192 CLYPELTPYKPWLKFLCVKLIIFASYWQSIIIQGLVVTGKL--------GTGNQDRTSGYV---Y 245

  Fly   317 QNFFICIEMLFAAIALRYAFPYQVYARSCISDGHGRSVTMQSISSSLKETMNPKDIMTD------ 375
            :|..:||||:..||....|||:..|....|..|    ..|:.| .:||:.:...|::.|
Yeast   246 KNGLLCIEMVPFAILHAVAFPWNKYTAFSIPYG----ARMKFI-YALKDFLGCGDLIWDFKQTLF 305

  Fly   376 ------AIHNFHPQYQQY--TQYSSG---------------GKNSRGIRVSSYD----------- 406
                  ...||.|:....  |:..||               |:||..:...|.|
Yeast   306 AGPLYYNYRNFDPEAMDLLSTRQQSGATMERLKHGLRFTDNGRNSYWVAYGSIDNNLVPESIEES 370

  Fly   407 -----------PDDPS 411
                       |:||:
Yeast   371 WEDDIAGQRTFPEDPN 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmep	NP_001097474.1	Solute_trans_a	66..341	CDD:460991	91/283 (32%)
HFL1	NP_012977.3	Solute_trans_a	14..270	CDD:460991	91/283 (32%)