Protein Alignment Tmep and tmem184a

DIOPT Version :10

• Sequence 1: NP_001097474.1
• Gene: Tmep / 38185
• FlyBaseID: FBgn0035236
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_998685.2
• Gene: tmem184a / 406841
• ZFINID: ZDB-GENE-040426-2925
• Length: 420
• Species: Danio rerio
• Alignment Length: 500
• Identity: 253/500 - (50%)
• Similarity: 307/500 - (61%)
• Gaps: 95/500 - (19%)

  Fly     1 MSTTAASLIEAALNASSGNATATTAGSLEATGKPNYVVQVKNTPMSTPLDPLLH----------- 54
            |:.|...::.|:.:.:..|...           |:|.:...||       .||:
Zfish     1 MNETTLRILSASSDKNMDNVPL-----------PSYSLLSNNT-------DLLNKTVIRSANGTE 47

  Fly    55 --VGDGIFLQTKTAQVLAGVCVWAALFITCQQIYQHLRWYTNPQEQRWIVRILFIVPIYATYSWI 117
              ..|.|||.|.|||.|:|:.||:||.:||.|||.|||.||.|.|||:|:||||||||||..||:
Zfish    48 VVADDQIFLSTATAQALSGIFVWSALILTCHQIYLHLRSYTVPNEQRYIIRILFIVPIYAFDSWL 112

  Fly   118 SLLFFNSDNVYIYFFTVRDCYEAFVIYNFLSLCYEYLGGEGNIMSEIRGKPIKTSCLYGTCCLKG 182
            ||||..:|..|:||.:||||||||||||||||.:||||||..||||||||||::|||||||||.|
Zfish   113 SLLFITNDQYYVYFDSVRDCYEAFVIYNFLSLSFEYLGGESAIMSEIRGKPIQSSCLYGTCCLVG 177

  Fly   183 KTYTIGFLRFCKQATLQFCLVKPLVAFIIIFLQAFGHYHDGDWSADGGYIYITIIYNISVSLALY 247
            .:|:|||||||||||||||:|||::|.|.|.|||||.|||||::..|||:|||||||.|||||||
Zfish   178 MSYSIGFLRFCKQATLQFCVVKPIMAVITILLQAFGKYHDGDFNVTGGYLYITIIYNFSVSLALY 242

  Fly   248 GLYLFYFATRDLLTPFEPVLKFCTIKSVIFLSFWQGVGLAILEKANVI--SPIVDSAGTVTVEPG 310
            .|:||||||.|||.||||||||.|||||||||||||:.|||||:..||  :..:|..   .|..|
Zfish   243 ALFLFYFATSDLLRPFEPVLKFLTIKSVIFLSFWQGMVLAILERCGVIPEAQFIDGH---EVGAG 304

  Fly   311 TVSAGYQNFFICIEMLFAAIALRYAFPYQVYARSCISDGHGRSVTMQSISSSLKETMNPKDIMTD 375
            ||:||:|||.|||||.||:|||||||...|| |...::.......|..|||.||||:||.|::.|
Zfish   305 TVAAGWQNFIICIEMFFASIALRYAFTSSVY-REKKNEAPENVAPMHGISSGLKETINPGDMVQD 368

  Fly   376 AIHNFHPQYQQYTQYSSGGKNSRGIRVSSYDPDDPSSGAAAGGMQASQPTSGGYDAVATGPGSGG 440
            |||||.|.||||||.|:                          .:..||::.|...::|
Zfish   369 AIHNFSPAYQQYTQQST--------------------------QEVVQPSANGKPGIST------ 401

  Fly   441 NGGSNCMASKTLGNQRKFQPGGQRVATISQNYNEKTMLLSSDDEY 485
                    ||                  |...::|.||:.:|||:
Zfish   402 --------SK------------------STKKSDKVMLIDTDDEF 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmep	NP_001097474.1	Solute_trans_a	66..341	CDD:460991	196/276 (71%)
tmem184a	NP_998685.2	Solute_trans_a	61..335	CDD:460991	196/276 (71%)