Protein Alignment CG7879 and rbm12b.3

DIOPT Version :10

• Sequence 1: NP_647626.1
• Gene: CG7879 / 38184
• FlyBaseID: FBgn0035235
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: XP_002934460.2
• Gene: rbm12b.3 / 100491658
• XenbaseID: XB-GENE-22063331
• Length: 659
• Species: Xenopus tropicalis
• Alignment Length: 1027
• Identity: 206/1027 - (20%)
• Similarity: 330/1027 - (32%)
• Gaps: 412/1027 - (40%)

  Fly     1 MSVIIRLQNLPWTANARDIRNFFSGLSIPEGGVHIIGGEMGDAFIAFSTDEDARCAMLKDREKLM 65
            |:|:||||.||..|.:.|||:|||||.||:|||||.||::|:|||.|:||||||.||.:....:.
 Frog     1 MAVVIRLQGLPVVAGSTDIRHFFSGLHIPDGGVHITGGKIGEAFIIFATDEDARRAMSRSGGFIK 65

  Fly    66 EIQVRLLLSSRAEMQKVIETARKAASAQAPVSVPVPMPVVVPVTAAKVAGPAAPLPPIIGGLNTF 130
            :.::.|.|||:||||..:|..||                     ..|..||...:..::..:.
 Frog    66 KSRIELFLSSKAEMQHTLEMNRK---------------------GNKDLGPTPDISKLLNVMK-- 107

  Fly   131 LGQGQVKGVATGTVPSFLTYQQQAGITLSDVTGRRSRSRSSSSDDSDRERERDRQRERERGRKRR 195
                  ||:          ||:
 Frog   108 ------KGI----------YQK------------------------------------------- 113

  Fly   196 SDRLDKSQERELKMVAGGGALPSPWAQPPQNQLPAVGLGLNMGLNLNLPQIPSLQSYTTSTTTTN 260
                                                                            |
 Frog   114 ----------------------------------------------------------------N 114

  Fly   261 VTNNYNLEPSATSVQLLTALQQVSSGSAAPAQPSKSESEPIAFASVNPYAQMYPQLFQQQQMLLQ 325
            :.|..|:|....           |||:.                            :.::.|...
 Frog   115 MANKSNVEAGFD-----------SSGAK----------------------------YTEENMPRP 140

  Fly   326 QQQTQAKVSPTMGGSPGGGSTPQVVADTCYIRMSGMCQNTSYSDIRKYFQGMYIP--HNGIKIMM 388
            :.|.:..:.|......|            |:.:.|:....|..|::::|.|..:.  |..::
 Frog   141 KYQGKKDIWPLKDNGYG------------YVFLYGLPYTASELDVKEFFHGFNVVDLHFSVR--- 190

  Fly   389 VNGSRTGVAYVEFSRVSSAQKAVQRNNTMFRDRLIQI--------VPVGDDEFEMAEE-RASRQ- 443
            .||.|.|.|||:|..|..||.|:.|:|.....|.|.:        :..|....|..|. |.:||
 Frog   191 QNGVRDGNAYVKFGSVQDAQAALSRDNEYIGHRYICVKLCNEQKWIEAGGPTDERNESVRKNRQW 255

  Fly   444 -------GQDGSRSHGNHNGGDRGERGGGAPVPVPRPVTNVLYIEDLPQTTTEQDIMKMFSASYT 501
                   ....|||...|....|.          |......|::.::..:..:.|| |:|.....
 Frog   256 SPRFPSKNHSRSRSPKIHRTRSRS----------PHNQQFYLHLLNMSYSVQKTDI-KLFFGDPD 309

  Fly   502 VVD----ILLSPSPKNRRESVAFVLFAREAEADSALQDTSKHYIGFRQLRVRSSSEEDMQNAKEK 562
            :.|    :||..:....||  .|||...|......| ...|..:..|::.|...:.:||.
 Frog   310 IPDTQIKLLLDRNGVQTRE--GFVLIKNEKFYQKCL-GLHKGLLNGREVWVYPIARKDML----- 366

  Fly   563 QRRANEQLLKEEADQREELLKDQQRRQKQQQQENENIQANRFAADPRRRQAEDQQQQQQMNMGPN 627
                             ||::..:|:|.::
 Frog   367 -----------------ELIESSERQQLER----------------------------------- 379

  Fly   628 FNSNMSPNMMAPFVNGGNMPFHMPPLQQNGVNNFPFNMNNN---YNYNGNSNGNGPNYPNDNGGA 689
             |::..|:....|.:..|:..:|      .:.|||||::.:   ..:.|        :|.|
 Frog   380 -NTSEDPSPKKKFRDRSNLKRYM------YLRNFPFNVSKSEVQKFFAG--------FPVD---- 425

  Fly   690 GVIQRPRQEDVFVRVHNCEYATRANDLGE---LFSLEHLRIEHIEQLFNERNQSSGEFIV-EFSD 750
                   ::|:|:.     |.:|...|||   .|..||..|  :.:..|::.....|.:: ..|:
 Frog   426 -------EQDIFLL-----YDSRGVGLGEALVTFPSEHQAI--LAEGLNQQKFLGTEVLLRRISE 476

  Fly   751 PASCKL-AIREFHNRR--FRGRGLRVVAITPQ----EIADRMKKPFMDYLPGGNGPRKAETNNAN 808
            ....:| |..|.||.|  .|....|...:.|.    |::|...:.:       :.||....::..
 Frog   477 EQMKELGAFPEDHNEREPKRSTSYRDEYLEPAEQGFEVSDYGHRSY-------DQPRPYRDDDFG 534

  Fly   809 DGAGGNKASAQPSRRRGPSRFDKPQEQPSQQQDRPLSLEREDNSSTS--SNAPVKQHFNPFARPD 871
            .|:|        |.||.|.|...|.:   ..||.|.......|.:..  .:.|:
 Frog   535 HGSG--------SIRRSPERLRSPYD---MNQDEPYGRFHMGNQNVEDYKSGPI----------- 577

  Fly   872 PPLSSSSLSPSNQGQVKPTSPVPVPTSIIPDKFNRP---GCVVAMRNVPFKAELKDIMRFFSDYK 933
                                             |||   |..:.::|||:.|.:::|:.||..|.
 Frog   578 ---------------------------------NRPRSGGASIRLKNVPYTATIEEILDFFYGYN 609

  Fly   934 LSPDDIIRRFNDEGKPTGDTRVAFESPSEARSAFESRRKKQIFNRTVYLDII 985
            :.||.:...:|.:|...    |..|:..||.:|.....::.|..|.|::.||
 Frog   610 VVPDSVEMDYNCKGTAI----VHMENYDEAAAAVNELNERPIGPRKVHMSII 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7879	NP_647626.1	RRM1_RBM12_like	2..75	CDD:409932	40/72 (56%)
		RRM_hnRNPH_ESRPs_RBM12_like	355..425	CDD:409699	23/71 (32%)
		RRM_SF	478..549	CDD:409669	17/74 (23%)
		RRM_SF	700..773	CDD:409669	20/79 (25%)
		RRM5_RBM12_like	909..983	CDD:409937	20/73 (27%)
rbm12b.3	XP_002934460.2	RRM1_RBM12B	2..80	CDD:410139	44/77 (57%)
		RRM_SF	158..240	CDD:473069	23/84 (27%)
		RRM_SF	285..365	CDD:473069	18/83 (22%)
		RRM_SF	399..474	CDD:473069	22/106 (21%)
		RRM_SF	585..657	CDD:473069	20/75 (27%)