Protein Alignment CG12099 and rnf10

DIOPT Version :10

• Sequence 1: NP_647623.1
• Gene: CG12099 / 38181
• FlyBaseID: FBgn0035232
• Length: 708
• Species: Drosophila melanogaster
• Sequence 2: XP_012814046.1
• Gene: rnf10 / 395022
• XenbaseID: XB-GENE-854662
• Length: 754
• Species: Xenopus tropicalis
• Alignment Length: 815
• Identity: 259/815 - (31%)
• Similarity: 372/815 - (45%)
• Gaps: 187/815 - (22%)

  Fly     1 MDSNNSSNSKKQPQSSHHGKSSSAESQRKSSELHTNSNKQRHSRRRNQVPTPRNDQ---QQQPQQ 62
            ||..:::.:|.|.:|...|  .|.||:.||...:.||:|||::|:|.. ..|:|:.   |.:...
 Frog    12 MDPGSANANKNQNRSGSAG--PSGESKPKSEPKNGNSSKQRYNRKREN-SYPKNETFAGQSRRSC 73

  Fly    63 PAKLRPNVDKRPKARGFGGGYDFPSPRGQDGASGSSRLAYSATGYSRSGDFDHELNSVYTQGSKK 127
            |.|.: ..:|.|..|  ||...:...|.::.|. :.|..:|:..||               |.||
 Frog    74 PQKSK-TFNKVPPQR--GGPKQYGMGRREEVAE-TQRAEFSSAQYS---------------GPKK 119

  Fly   128 QNLNHLLNFHCVPRELERGHHHQAQQHHGLSGRKQR-----YNKEQFLQANFQFVIRSGAKAQVN 187
            .||||||||...||     .|......:|..||:.:     :|||.|||||.|||:.......|:
 Frog   120 INLNHLLNFTFEPR-----GHPGGLNGNGNFGRRHKWGNKPFNKELFLQANCQFVVSDDNDYSVH 179

  Fly   188 -GSPDALIDWSYIEQINIQTTEELQCPICLYPPVAAKLTRCGHAYCWPCLLHYLSLSDKTWRKCP 251
             ..||.|:.|.::||:.|.:.|...||||||||||||:|||||.:||.|:|||||||:|.|.:||
 Frog   180 FADPDTLVSWDFVEQVRIFSHEVPSCPICLYPPVAAKITRCGHIFCWACILHYLSLSEKDWSRCP 244

  Fly   252 ICYDAIHAGDLKSCTIEQLRDLQVGEKITFQLMRRRKGS---------MYIEN--HVAGLGETIE 305
            |||.::...||||....:.....||:|||.|||||.||.         |.::.  |:..|..|:
 Frog   245 ICYSSVIKKDLKSVVTTETHLYSVGDKITMQLMRREKGVLVAMPKSKWMKLDEPIHLGDLDHTL- 308

  Fly   306 RFPFVSAGEEAKRYSKFLIAKRMDV-AAIIERERNELLAE--SDVSCPEDVFIQQALVMLQER-- 365
                         |||.|:|.|..: :.:|..|:..||.:  ::...||..||:.|:..||:|
 Frog   309 -------------YSKLLLASRDQILSQVIGEEKVALLEQYNAEKETPEACFIEAAMQELQDRAG 360

  Fly   366 ----------------VEKLGVEKPDPKED--------------EEETAPVLCLE---TETK--- 394
                            :|.|..|....|:.              ||||....|.:   ||:.
 Frog   361 NLCAASKPEIEAATLSMEALNFESTSDKQHTVLEREVVHYISAFEEETMEPPCEDCSPTESSPPD 425

  Fly   395 ------IDIEKSDDA---SISSGEASSSLSYSSNHNKYYYFYQSNDGQNIYLHPLNVKMLQACYG 450
                  .|:..:.|.   |:|..|:.........::.||||||:.|||::||||:||:.|...||
 Frog   426 ITAVLATDVSTATDGGLPSLSQQESKPENCGPLGNSHYYYFYQAVDGQHVYLHPVNVRCLVHEYG 490

  Fly   451 TLDLGPLLIEAQIVQMEQHSMDEEHRRKFTCLGHLPLTCQFSVVEVELQPPVVTGGILKLFKEDI 515
            :|:..|..|.|.:|:|:..:|.||.||:...|.||||||:||:.|:.|.||.|:...|:||..::
 Frog   491 SLERCPEKITATVVEMDGFTMTEEVRRRHRYLCHLPLTCEFSICEMALGPPDVSVDTLELFTAEV 555

  Fly   516 LHRKKERQRRDREERKREQHINEINDRQMGKLIASAANLDLSSSHEFP--------------TCG 566
            ..||:.|||:.|:|::||:.|....:::.|  |...|.:.|.:..:||              |..
 Frog   556 EKRKRLRQRKARDEQRREKRIELEENKKQG--IYPEARIALENLQQFPAFSSSPIDSLFNVETQN 618

  Fly   567 FEEALP------APSGSVPMNISNQDP-----GSRYSS----VTLGSPKQEMWPTIGSNSPGGGG 616
            |....|      :.|||:.....:.||     .||..|    :.:|..|.|.||.         .
 Frog   619 FISVSPLSCSPTSQSGSLLGAECSSDPLLTEDESRCPSFAQMLRVGKAKPETWPK---------A 674

  Fly   617 APLDVQVGAWGRSAPPPPRAVMVPRTSDEDFE------------QRSVGHWGLGELLVGALDQKK 669
            ||.:|            |...:.|..:|.|.|            |.|...         |::...
 Frog   675 APKNV------------PENTLTPANADSDVESDCSERVPVPSFQNSFSQ---------AMEAAF 718

  Fly   670 QKVGAAKSNGAAPAESKKQKKAKGKKMVPLFATGM 704
            .|:.||.   ..|...:|..|.|.|:...||:|.:
 Frog   719 LKLDAAL---PTPPSVEKGGKKKKKQQKLLFSTSI 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12099	NP_647623.1	RING-HC_RNF10	211..263	CDD:438198	35/51 (69%)
rnf10	XP_012814046.1	RING-HC_RNF10	203..256	CDD:438198	35/52 (67%)