Protein Alignment: CG12099 and SPBP8B7.23

• Sequence 1: NP_647623.1
• Gene: CG12099
• FlyBaseID: FBgn0035232
• Length: 708
• Species: Drosophila melanogaster
• Sequence 2: NP_596530.1
• Gene: SPBP8B7.23
• PomBaseID: SPBP8B7.23
• Length: 673
• Species: Schizosaccharomyces pombe
• Alignment Length: 771
• Identity: 178/772 (23%)
• Similarity: 320/772 (41%)
• Gaps: 181/772 (23%)

  Fly     1 MDSNNSSNSKKQPQSSHHGKSSS--AESQRKSSELHTNSNKQRHSRRRNQVPTPRNDQQQQPQQP 63
            |.||::|:||...:|.:...|||  ..|..|:.|...:....|:|.::.|....:|.|....::.
pombe    12 MPSNSNSSSKLNAKSPNFIPSSSNIPRSSAKTKEHSADRKPHRNSEKKTQGMPRKNQQLASSERK 76

  Fly    64 AKLRPNVDKRPKARGFGGGYDFPSPRGQDGASGSSRLAYSATGYSRSGDFDHELNSVYTQGSKKQ 128
            .|.:..::|:..|.....|.....|:               |.|      |..|..:.:..:.|:
pombe    77 TKNKKRLEKQSSAIADSIGESLDDPQ---------------TVY------DEHLFDILSARTNKR 120

  Fly   129 ---NLNHLLNFHCVPR----------ELERGH--HHQAQQHHGLSGRKQRYNKEQFLQANFQFVI 178
               ||||||||...||          ...||:  :.|...||.:       :|.:::.||::||:
pombe   121 GQINLNHLLNFQFTPRTNSNAFSAPPRRSRGYNTYGQGSGHHPM-------DKSRYVNANYRFVV 178

  Fly   179 RS-GAKAQVNGSPDALIDWSYIEQINIQTTEEL-QCPICL-YPPVAAKLTRCGHAYCWPCLLHYL 240
            .. |........||:.:.|..:.|:...:..:| .||.|| ..||||:::||||.||:.|||.::
pombe   179 SPIGDYQSQKLDPDSPVKWEDVWQVLCSSDFQLAACPFCLEEKPVAARMSRCGHVYCFSCLLRFV 243

  Fly   241 SLSDKT----------------WRKCPICYDAIHAGD---LKSCTIEQLRDLQVGEKITFQLMRR 286
            ......                .|.||||:|:|...|   ::....::.:.|:.|:.:..:|.:|
pombe   244 ETPTAAEVKAAETSGTKIVKCGHRSCPICWDSIRLRDVHPIRWVEDKEFQKLEEGKSVCLRLYQR 308

  Fly   287 RKGSMYIENHVAGLGETIERFP-------------------FVSAGEEAKRYSKFLIAKR--MDV 330
            ..||             |..||                   |..:|   ..|::.:|...  |..
pombe   309 NNGS-------------ILAFPRSCRSFALDGSFHSDEIPNFTMSG---AAYARIIIGSHDYMVQ 357

  Fly   331 AAIIERERNELLAESDVSC--PEDVFIQQALVMLQERVEKL--GVEKPDPKEDEEETAPVLCLET 391
            ..::|.|:.:.:|..|:|.  ..|.:.::...:|.:|:..|  .|.:.:.|..:.: ...|||::
pombe   358 QHLLEIEQLQQIAAEDISLYGSADTYYERITQILLDRISSLSESVNEQNIKSLQTD-IDNLCLQS 421

  Fly   392 ETKIDIEKSDDAS-ISSGEASSSLSYSSNHNKYYYFYQSNDGQNIYLHPLNVKMLQACYGTLDLG 455
            .:...:.:.||.: :|..|.:.:          |.|||.....:|||.||::::|::.:|:.:..
pombe   422 NSLKQLSEVDDLNDVSGSEIADA----------YLFYQPFAHSHIYLSPLDIRILKSAFGSYENF 476

  Fly   456 PLLIEAQIVQMEQ-HSMDEEHRRKFTCLGHLPLTCQFSVVEVELQPPVVTGGILKLFKEDILHRK 519
            |..:..::.::.. |.::.|.|::|..:.|||..|:.:.:|.:.. .::...:|..||.:|..|:
pombe   477 PDELVPRVERISSGHLVNSELRQRFKYMAHLPEGCEVAFIECDWS-KIIPKEVLLTFKSEISKRR 540

  Fly   520 KERQRRD-REERKREQHINEINDRQMGKLIASAANLDLSSSHEFPTCGFEEALPAPSGSVPMNIS 583
            |:|:.:: ||||.|::     .:|...:.|.|..|:                    ...||..:.
pombe   541 KQRKAQEMREERYRQR-----AERDTEEQIYSELNM--------------------QRPVPKTVV 580

  Fly   584 NQDPGSRYSSVTLGSPKQ-EMWPTIGSNSPGGGGAPLDVQVGAWGRSAPPPPRAVMVPRTSDEDF 647
            ::||...:.  ||||..| |....:.::.     :.|......||..|       :....:|.|
pombe   581 HEDPAEAFP--TLGSHHQFESTDEVNTDE-----STLSTAKTVWGTRA-------LANIQNDTD- 630

  Fly   648 EQRSVGHWGLGELLVGALDQKKQKVGAAKSNGAAPAESKKQKKAKGKKMVPLFATG 703
            :|..:..|.:....|..|              :||:::.|.||   ||.:.|.:||
pombe   631 DQDDLDGWKVDWDKVAQL--------------SAPSKNSKNKK---KKKLVLLSTG 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12099	NP_647623.1	zf-C3HC4_2	212..253	CDD:290634	21/58 (36%)
SPBP8B7.23	NP_596530.1	RING	214..272	CDD:214546	21/58 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	151	1.000	Inparanoid score	I1277
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0004207
OrthoInspector	1	1.000				T1125852
orthoMCL	1	0.900				OOG5_127918
Panther	1	1.100			LDO	PTHR12983
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1987
TreeFam	1	0.960
	10	9.960