Protein Alignment SA2 and stag3

DIOPT Version :10

• Sequence 1: NP_612109.3
• Gene: SA2 / 38167
• FlyBaseID: FBgn0043865
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: XP_073778477.1
• Gene: stag3 / 100333021
• ZFINID: ZDB-GENE-140106-130
• Length: 1106
• Species: Danio rerio
• Alignment Length: 1062
• Identity: 254/1062 - (23%)
• Similarity: 433/1062 - (40%)
• Gaps: 243/1062 - (22%)

  Fly    12 NDSQASNQMDFEIREECSIAPNDEPVCVDGTVGDAT----NKSLLQMILSRKRLSPTNKR----- 67
            :||.:....|||.:.:.|...      |:.|.|.|:    ::.....:.|.:..:||:..
Zfish    10 DDSISLTGSDFEFQLKTSKRK------VNSTQGVASPNRVHRRPASALSSSQSQAPTDSEGGVST 68

  Fly    68 ----------NSHIESVAKYWGEFYLDSPTAALVALLQFVVEVSGSHYQIPDDTSMPFSYSDILS 122
                      .|.:.:|...|.|.|.....|.|:.|:.|||:.||....:..:.......:||:|
Zfish    69 AYLYEAVRSGRSALTTVIDDWLEEYQRDKEAGLLELINFVVQCSGCKGVVSREMLSSLQNADIIS 133

  Fly   123 NSSSHFSNTHI-YPLI------RKPADVFVNQVGSFLNALL------LVANKFRSDSYQLFLVQL 174
            :.:..|:...: |||:      |:    |...|..|:..|:      |:.:.|...|   |:..|
Zfish   134 HLTKEFNEDSVSYPLVSSGPQWRR----FSEGVCEFVCVLVRGCRNTLLYDDFLFSS---FIALL 191

  Fly   175 TNFVMACSESNIRTFRHTATMIGLKIMTIL-----------------SDL--------KSLD--- 211
            |..    ::|.:|.||||::.|.:::|:.:                 |||        :::|
Zfish   192 TGL----ADSQVRAFRHTSSFIAMRLMSSIVSVAADVNIQAQMIQRRSDLEKSKPAEERAIDRLE 252

  Fly   212 ------------DEIAMTVWMQMFNSMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLR 264
                        .|...::...:|..:||.|.||::.:||.:|:.|:|.|....|...|....|:
Zfish   253 ELEHSYRELMEQQEDLRSLMNGIFKGVFVHRYRDVIPEIRAVCMEEMGVWLRENPAHFLNDEHLK 317

  Fly   265 IFYEALNDGSGDV-IQCSLDNISVLCRKDVLFSEIVALTSEFREILVELCLGKEDAIAEKSVQFL 328
            .....|:|....| :||.|....:...||.| |.:...||.|:|.::.:.|.|:..:|.::|:.|
Zfish   318 YVGWMLHDKQAAVRLQCVLTLQKLFEEKDFL-SRLEFFTSRFKERILCMILDKDSDVAVETVKLL 381

  Fly   329 THFHVLSAEILTDDVCRVLEQ-----LIMAANRGLAQAAADLFILRRNGLDGETFC--------Q 380
                 |..:..|||.....|:     |:.|.:|||| .||..|:.       .|.|        .
Zfish   382 -----LLIQTQTDDGLSASERAAVYPLVFATHRGLA-CAAGRFLY-------HTLCCAADQSSDS 433

  Fly   381 RVKHLLQL----FIECG-HEQADYLVDSLID--NCELVLDWKSMIAVLLENPKSRELSDIHCSSL 438
            |...:|:|    ||:.. |:.|.||||||.|  ..|| .||:.|.::||::...:|..:   |:|
Zfish   434 RSVSILRLLALFFIQSEYHDHAAYLVDSLWDVAGAEL-KDWELMTSLLLQDSSLQEQLE---SAL 494

  Fly   439 IAILLAGVKQATAGEIPPGR-YTKDL-KREPRQGAQE--RATKCLAPVLPELLRTYANRLQDIER 499
            |.|::..|:||.....|..| :.|.: .|:.|..||:  |.:....||||:||..::..:..:.|
Zfish   495 IDIMMCAVRQAAEATPPTARAHRKSVTARQKRVQAQDQRRISSVFMPVLPQLLAKFSADVGKVSR 559

  Fly   500 LLELPKYFCFDYYHEQNRMGQ-LNELVEHFELIIFDQTSSTTVLQITVK-----TLEFLNRMIPI 558
            ||..|.:|..:.|....|:.: |::|:             :.|..||:|     .||...|::.:
Zfish   560 LLRAPLHFQLEVYGTSGRLEKSLDQLL-------------SQVCDITLKHHEECVLEACVRVLCV 611

  Fly   559 PLTK-------------QLLNSAVTNYKMAWHRTQDTSPSRSTHNESNRLLATLRLLTVLSGHFN 610
            ..::             |||::.|..:..   ..::.....:..::..|..::|.:|.:.|
Zfish   612 LCSEGYTFCGRAETAVGQLLDTTVEKFTA---NLEEILQGSADEDDLYRAASSLNILAIFS---- 669

  Fly   611 LSKWDLTEPLLFSLKMLLRQRRLPNGDDLPPEAFSLYLKACFCC---LCWDMENLEGTALNNVDM 672
             |..||||..||.....|.:..:..|:    .:..|.:.|..||   |.|..........:..:.
Zfish   670 -SARDLTERNLFEFCFQLLKMGVETGE----ISEKLMVPALSCCAYQLLWSAHRNTQRRTDKAEA 729

  Fly   673 DEYCDVLHHNLEDYLYVTFSLVGKS----NTEPLAYPCFSYTCDLFVLHGNLC----GSSNPSIR 729
            ......||         :|.::.:|    ...|:....|...|||.::   .|    ||.:|
Zfish   730 RRVLKSLH---------SFCVLCQSCLSIALSPVRSKAFVCVCDLLLV---FCRPPEGSISP--- 779

  Fly   730 SVAHVPSGNELDILEGFLMEHFLELSPSDLMLE--------TNSDQ------LQRIRSILTSYLK 780
                         |:.|..:..|....:..:|:        |..|:      ||: |:.|:.|.|
Zfish   780 -------------LQRFSPDESLRAEMASFVLDYVFGDEDLTGEDEEMMTALLQK-RNHLSGYCK 830

  Fly   781 VVCLGVVPTMRASKFYEYYVKYHAPFGDVMRCSMELALQRNPIHFAMTMLHTCLLLYAKVFPDDT 845
            ::..||:....|:....||.:::..|||:::.::..:...|....|.|:......|||.:   |.
Zfish   831 LIIYGVLELQAATDILRYYHRFYKDFGDIIKETLNKSKMINSEDSARTVCLCLQQLYAGL---DL 892

  Fly   846 RHAAGQRALRPAEFSELMELANRLAKILISNPMEHRECVIALHRSGILFVFELAQKQPTEATKKL 910
            :...|       |..|:..||.:||.....|....|:.:::||:.||.|..:..:|  .|| ..|
Zfish   893 QCCDG-------ELMEIRLLAKKLAMNFSINLRLVRKPLLSLHQDGIRFASQGLEK--GEA-MNL 947

  Fly   911 PFLRVLKVFVPLLLVQDKTRIL 932
            .||.:|..|...||..::.::|
Zfish   948 QFLEILSEFSFKLLQPERKQLL 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA2	NP_612109.3	IRR1	<115..>329	CDD:227824	64/267 (24%)
		STAG	132..>215	CDD:462502	27/135 (20%)
stag3	XP_073778477.1	None