Protein Alignment SA2 and stag1

DIOPT Version :10

• Sequence 1: NP_612109.3
• Gene: SA2 / 38167
• FlyBaseID: FBgn0043865
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: NP_001121432.1
• Gene: stag1 / 100158523
• XenbaseID: XB-GENE-1006155
• Length: 1265
• Species: Xenopus tropicalis
• Alignment Length: 999
• Identity: 237/999 - (23%)
• Similarity: 434/999 - (43%)
• Gaps: 148/999 - (14%)

  Fly    69 SHIESVAKYWGEFYLDSPTAALVALLQFVVEVSGSHYQIPDDTSMPFSYSDILSNSSSHF-SNTH 132
            |.::||...|.|.|......||:.|:.|.::.||....:..:.......::|:...:..| .::.
 Frog   103 SAMQSVVDDWIESYKQDRDIALLDLINFFIQCSGCKGTVRIEMFRNMQNAEIIRKMTEEFDEDSG 167

  Fly   133 IYPLI------RKPADVFVNQVGSFLNALL------LVANKFRSDSYQLFLVQLTNFVMACSESN 185
            .|||.      :|    |......|::.|:      ::.:::..|:       :.:.:...|:|.
 Frog   168 DYPLTMPGPHWKK----FRCNFCEFISVLIRQCQYSIIYDEYMMDT-------VISLLTGLSDSQ 221

  Fly   186 IRTFRHTATMIGLKIMTIL-----------------------------------------SDLKS 209
            :|.||||:|:..:|:||.|                                         .:|:.
 Frog   222 VRAFRHTSTLAAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQE 286

  Fly   210 LDDEIAMTVWMQMFNSMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLRIFYEALNDGS 274
            ..|||. .:...:|..:||.|.||.:.:||.:||.|:|.|...|....|..:.|:.....|:|..
 Frog   287 NQDEIE-NMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQ 350

  Fly   275 GDV-IQCSLDNISVLCRKDVLFSEIVALTSEFREILVELCLGKEDAIAEKSVQFLTHFHVLSAEI 338
            |:| ::| |..:..|.....||.::...|:.|::.:|.:.|.||..:|.::::.:|.....|.|.
 Frog   351 GEVRLKC-LKALQSLYTNRELFPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEA 414

  Fly   339 LTDDVCRVLEQLIMAANRGLAQAAADL----FILRRNGLDGETFCQR----------VKHLLQLF 389
            |:::.|..:..|:.:|:|.:|.||.:.    ...|.:....|...:|          ||.|:..|
 Frog   415 LSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRSSPNGNLVKMLVLFF 479

  Fly   390 IECG-HEQADYLVDSLIDNC-ELVLDWKSMIAVLLENPKSRE--LSDIHCSSLIAILLAGVKQAT 450
            :|.. ||.|.||||||.::. ||:.||:.|..:|:|.|...|  :|:...|:||.:::..::||.
 Frog   480 LESELHEHAAYLVDSLWESSQELLKDWECMTELLVEEPMQGEEVMSERQESALIELMVCTIRQAA 544

  Fly   451 AGEIPPGRYT-----KDLKREPRQGAQERATKCLAPVLPELLRTYANRLQDIERLLELPKYFCFD 510
            ....|.||.|     ...:|:.:...:.:.|:.....||.||..|:...:.:..||::|:||..:
 Frog   545 EAHPPVGRGTGKRVLTAKERKTQLDDKNKLTEHFIVALPVLLSKYSADAEKVANLLQIPQYFDLE 609

  Fly   511 YYHEQNRMGQLNELVEHFELIIFDQTSSTTVLQITVKTLEFL--------NRMIPIPLTKQLLNS 567
            .|........|:.|::....:: ::...:.||:...||...|        || :.| ...||::.
 Frog   610 LYSTGRMEKHLDSLLKQIRFVV-EKHIESDVLEACSKTYSILCSEEYTIQNR-VEI-AHSQLIDE 671

  Fly   568 AVTNYKMAWHRTQD--TSPSRSTHNESNRLLATLRLLTVLSGHFNLSKWDLTEPLLFSLKMLLRQ 630
            ....:.   |..::  .....:..:|...::|:|:.||......:|:||:    |..|...|||.
 Frog   672 LADRFS---HAVEELLQEAEEADEDEIYNVMASLKRLTCFHNAHDLTKWE----LFVSCYRLLRA 729

  Fly   631 RRLPNGDDLPPEAFSLYLKACFC---CLCWDMENL-EGTALNNVDMDEYCDVLHHNLEDYLYVTF 691
                 |.:.......:.::|..|   .:.|.:..: ||    |...:|.. .|...::.:|.|..
 Frog   730 -----GIEHEGMMEQIVVQALQCSHYSILWQLVKITEG----NPSKEEML-TLRKTVKTFLAVCQ 784

  Fly   692 SLVGKSNTEPLAYPCFSYTCDLFVL--HGNLCGSSNPSIRSVAHVPSGNELDILEGFLMEH-FLE 753
            ..: .|.|..:....|...|||.::  |....|.....:..|.:...|.:.::| .|:|:| |::
 Frog   785 QYL-SSVTTTVKEQAFMLLCDLLMIFSHQLTTGGRENLVLLVFNPDVGLQSELL-NFVMDHVFID 847

  Fly   754 LSPSDLMLETNSDQ-------LQRIRSILTSYLKVVCLGVVPTMRASKFYEYYVKYHAPFGDVMR 811
            ....:..:|.:.:.       |.:.|::|.::.|::...:|....|:..:::|:||:..:||:::
 Frog   848 QDDENQSMEGDEEDEANKIEALHKRRNLLAAFCKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIK 912

  Fly   812 CSMELALQRNPIHFAMTMLHTCLLLYAKVFPDDTRHAAGQRALRPAEFSELMELANRLAKILISN 876
            .::....|.:.|..|.|:    :|...::|.:..:..........|..|.:.|||.|.|.....:
 Frog   913 ETLSKTRQMDKIQCAKTL----ILSLQQLFNELVQEQGPNLDRTSAHVSGIKELARRFALTFGLD 973

  Fly   877 PMEHRECVIALHRSGILFVFELAQKQPTE-ATKKLPFLRVLKVFVPLLLVQDKTRILNFFEPY-- 938
            .::.||.|..||:.||.|.|:....:..| ....|.||.||..|...||.|||..:.::.|.:
 Frog   974 QIKTREAVATLHKDGIEFAFKYQNPKGQEYPPLNLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLT 1038

  Fly   939 EQLIIPTCNRNDI-AHLKEYRNAL 961
            :|::.   .|.|: ..|..|||:|
 Frog  1039 DQMME---RREDVWLPLISYRNSL 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SA2	NP_612109.3	IRR1	<115..>329	CDD:227824	58/268 (22%)
		STAG	132..>215	CDD:462502	23/135 (17%)
stag1	NP_001121432.1	IRR1	112..>405	CDD:227824	67/305 (22%)
		STAG	167..280	CDD:462502	20/123 (16%)