DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32333 and ROG1

DIOPT Version :9

Sequence 1:	NP_001261246.1	Gene:	CG32333 / 38142	FlyBaseID:	FBgn0052333	Length:	1499	Species:	Drosophila melanogaster
Sequence 2:	NP_011371.1	Gene:	ROG1 / 852733	SGDID:	S000003112	Length:	685	Species:	Saccharomyces cerevisiae

Alignment Length:	448	Identity:	83/448 - (18%)
Similarity:	153/448 - (34%)	Gaps:	138/448 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1042 ALPPTGKTKIVACHLPPPLKERQPIGAIDNPV--YHIYE------------------SLRPISTP 1086
            :|.||.:   :..|....:|    :|.::..|  ||:|:                  ::.|:|..
Yeast     2 SLTPTNE---ILFHYKSSVK----VGELERYVITYHLYDGEEIPPDLNLNSLWLKVRNMNPLSYR 59

  Fly  1087 AIFSNKPVLKSHSLAELKRPQNLPNHSINHHCKTHAINANGNVLENGLDHEQDEIKENSNGQVR- 1150
            |.:...|.:   ...::|..|       .||.:....:.:....|..:..:||.:.|.|...:|
Yeast    60 AAYLMGPFM---LYCDVKTAQ-------YHHSQKIVASVDYPKFEPNVQTQQDFVAELSVHNIRQ 114

  Fly  1151 --------TNKQGHGSNTNSKHKRKGQLASAVQEAPPSISLLEFEKYREEFRKQIKYQGSI--YS 1205
                    .::....:|||                                   :.|:.:|  ..
Yeast   115 KYVWIADVMSQILFTTNTN-----------------------------------VTYEVTIGTSK 144

  Fly  1206 DYVQLASELPYFYISDEYRAFSP-----------------------NGMHLVICVHGLDGN-SAD 1246
            :.|:...:||     ....::||                       ...|||:..|||..| |.|
Yeast   145 ESVENPHDLP-----SHLGSYSPKLTVNRLTTLDLWNLPVQITTPQKKKHLVVLTHGLHSNVSTD 204

  Fly  1247 LRLVRTYLELGLPGVNLEFLMSERNQGD---TFSDFDTMTDRLVTEILYHIDSCALNPARISFVA 1308
            |..:...:.........|.::.:..:|:   |......:..||...|:..:...::.  :||||.
Yeast   205 LVYIMEQIYKAQKNYPHEQIVVKGYRGNVCQTEKGVKYLGTRLAEYIIQDLYDESIR--KISFVG 267

  Fly  1309 HSLGTIIVRSALAR---------PQMRPLLPRLHTFLSLSGPHLGTLYNTSGLVNMGMWFMQKWK 1364
            ||||.:|...|:|.         .::.|:     .|::|:.|.||.:.:....:.:.:.| ....
Yeast   268 HSLGGLIQAFAIAYIYEVYPWFFKKVNPI-----NFITLASPLLGIVTDNPAYIKVLLSF-GVIG 326

  Fly  1365 KSGSLLQLCMRDTTDMRNSFLYRLSQR---STLHHFK-NILLCGSSQDRYVPAHSARL 1418
            |:|.  .|.:.:..::....||.||..   ..|..|| ..:...:..|..||.::|.|
Yeast   327 KTGQ--DLGLENDVEVGKPLLYLLSGLPLIEILRRFKRRTVYANAINDGIVPLYTASL 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32333	NP_001261246.1	DUF3657	150..226	CDD:289180
		MhpC	1223..>1447	CDD:223669	51/236 (22%)
		DUF676	1227..1422	CDD:282860	51/232 (22%)
ROG1	NP_011371.1	DUF676	184..382	CDD:309968	48/207 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341326
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930