DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9119 and C11orf54

DIOPT Version :9

Sequence 1:	NP_612081.1	Gene:	CG9119 / 38124	FlyBaseID:	FBgn0035189	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001272996.1	Gene:	C11orf54 / 28970	HGNCID:	30204	Length:	315	Species:	Homo sapiens

Alignment Length:	314	Identity:	150/314 - (47%)
Similarity:	202/314 - (64%)	Gaps:	9/314 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 EKPLYVPPLSELQNVIQGALAANFANVNVSVGPCPDLKAKQFGLVESGLGGKPTLLEAGGPPFLL 79
            |...:||.|.||..|:|..|..|||:|.|||..||||..:.|.....|:.||..:.|.||.|:||
Human     5 EFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLL 69

  Fly    80 PLVQRDKLYNIAEITRKIQGPGTVFAVGAGAGPWPIRGSNCEGIFNLSV-NEKDELTNGSYTATV 143
            |||.:.|:|::.:|.::|:.|| .|.:||||||:...|.|.|.:..:.. :|.....||||.|.|
Human    70 PLVNQKKVYDLNKIAKEIKLPG-AFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHV 133

  Fly   144 RGEQEECVLEKIPHTEP----RCALLLNLFLSQGKPGQVLKITAKQRTGEQNFIECIRKGLENHY 204
            ......|:|||  ::|.    :||||.|||.|:|:||:|:::.||:|||..||:.|:|:.||.||
Human   134 NPADGGCLLEK--YSEKCHDFQCALLANLFASEGQPGKVIEVKAKRRTGPLNFVTCMRETLEKHY 196

  Fly   205 GDKVVGLGGIFLIKKGAAHQHVM-RDFSKTPINSDEEVNEWLKFYEMPAQLNAVGTLVTKEHDLD 268
            |:|.:|:||.|:|:||....|:| .:||..|:|||||||:||.||||.|.|..:...|:::...|
Human   197 GNKPIGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFD 261

  Fly   269 LRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPVATHKVGRD 322
            |||:|.|.||....|||||||||||||||..|...||.:.|:|:|..||.:|||
Human   262 LRLEHTHFFSRHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSIGRD 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9119	NP_612081.1	DUF1907	31..310	CDD:286069	135/284 (48%)
C11orf54	NP_001272996.1	DUF1907	21..303	CDD:312474	135/284 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158951
Domainoid	1	1.000	254	1.000	Domainoid score	I2068
eggNOG	1	0.900	-	-		E1_KOG4048
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8531
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2885
Isobase	1	0.950	-	0	Normalized mean entropy	S3572
OMA	1	1.010	-	-		QHG52343
OrthoDB	1	1.010	-	-		D375938at33208
OrthoFinder	1	1.000	-	-		FOG0006469
OrthoInspector	1	1.000	-	-		otm41460
orthoMCL	1	0.900	-	-		OOG6_107407
Panther	1	1.100	-	-	LDO	PTHR13204
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4717
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720