Protein Alignment Usp10 and usp10

DIOPT Version :10

• Sequence 1: NP_728554.1
• Gene: Usp10 / 38103
• FlyBaseID: FBgn0052479
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: NP_001006761.1
• Gene: usp10 / 448441
• XenbaseID: XB-GENE-966184
• Length: 805
• Species: Xenopus tropicalis
• Alignment Length: 813
• Identity: 250/813 - (30%)
• Similarity: 385/813 - (47%)
• Gaps: 174/813 - (21%)

  Fly   724 TNSAQHKKSTQSVSVTASPNSVNNGPGVGAAGKANYSHTTKTFTNQQHYQQQHYHTQNSY----- 783
            :|:..|:.:..:::...|..::.:|     :|.|:...|:.|...::..:::......||
 Frog   116 SNNVLHENNFDAINCQFSECAIPDG-----SGNADSDGTSGTGQRERKKKKKRPPGYYSYLEGVG 175

  Fly   784 ---NNNSSGGGSSSNSSSSSSNNQPQVRNYGTMKMPSSPVAWTAP----TPER-KNSQQAAAAPA 840
               :.....|.::|...:|.|.:.|.:..       ..|::.|:|    :|:. .:....|.:..
 Frog   176 DVPSETLVNGHANSTGLNSISTDDPDLAE-------DIPISTTSPRTCNSPDNFVDLNNEALSND 233

  Fly   841 AATASAAPVAITTVTTSTASITATPNQFQPETGSSSASPAVAAAQQQQPAAQQHAQAAQTGAAAA 905
            |:..:|...|.|.......|:|::.....| :.:...||...|.  .||.|     ...|.....
 Frog   234 ASMHNALDNARTAGQPEECSVTSSEQSCIP-SDNGRESPVRTAV--VQPFA-----GTDTTENLG 290

  Fly   906 PSKSHSNYASSKKHQSYEPVVLSSVVATSSSANP------QPQLNL---APPAPPASQNSSDSSQ 961
            .:...:..:|.:...|...|:|..|.:.|..|.|      |..::|   |...|||.
 Frog   291 VTNGQTLESSEEGTASNGVVLLPEVSSLSEEAKPEETSTAQAVVHLPGSASANPPAK-------- 347

  Fly   962 LSWASLFASNKPVAKVAPYEASKIAQQQPSHPVLQLAPPQPAQVAAAAPVAQLSSPPQNLPLPTA 1026
             ||||||.::||                                         ||..|     .|
 Frog   348 -SWASLFHNSKP-----------------------------------------SSTTQ-----VA 365

  Fly  1027 HQQSQLPAPVPAPTAPLVTPGALSYSAASAQAVPAPSPASASVKPLKPEPPRPVQQQLDEWTSKY 1091
            :.:::...||   |:|.||                  .....:|    |.|.||.:  |....|.
 Frog   366 YVETKNATPV---TSPQVT------------------EKQVEIK----EGPVPVSE--DPVAIKI 403

  Fly  1092 AEYLTRHKTNLASISLRPRGLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVLSEVK---- 1152
            ||.|...|.....:||:||||.|:.|:||||:.||||:.|.|.|:|::|||    |.::.:
 Frog   404 AELLEEVKLVHKPVSLQPRGLINKGNWCYINATLQALVACPPMYHLMKSIP----VYTKAQRPCT 464

  Fly  1153 -TPTVNAMMSFMTNFSSLPSGLRLRLNNLNKGSQSKGKDDFVGSDLQCDMAFEPTEIYKL---WN 1213
             ||.:::.:..|..|:::|.        |.|..|:.|:.  |..|::....|||..||:|   :.
 Frog   465 STPMIDSFVRLMNEFTNMPI--------LPKAKQASGEK--VIRDIRPGAPFEPAYIYRLLTVFK 519

  Fly  1214 DSREEHVEGRQEDAEEFLGYVLNKLNDEMLEVIKLIDKPTPQ------QNGQEPA---------E 1263
            .|..|  :||||||||:||::||.|::|||.:.||:   .||      .||.:|.         |
 Frog   520 SSLSE--KGRQEDAEEYLGFILNGLHEEMLSLKKLL---LPQNDKIHINNGPDPVSEKEEINKDE 579

  Fly  1264 PEDGGDVWQMICNNRNKGSVTRQTDFGRTPVSDIFRGELRSRLQREGEHSTDVIQPFFTLQLNI- 1327
            .|...:.|:.: ..|:|.|||||.||.:||::|||.|.:||.:.::....:..:||||||||:|
 Frog   580 QEGSDEEWEQV-GPRHKSSVTRQADFVQTPITDIFGGHMRSVVYQQSSKESATLQPFFTLQLDIQ 643

  Fly  1328 -EKAASVKEALEILVGRDQLEGVTGSKTKQEVVAWQQMTLEKLPVVLILHLKYFDY-RSDGCTKI 1390
             ||..:|::|||.||.|:.::|.| :||||||...:::|||:||.||:||||.|.: ::.||.|:
 Frog   644 SEKIRTVQDALESLVARESVQGYT-TKTKQEVEICRRVTLEELPPVLVLHLKRFVFEKTGGCQKL 707

  Fly  1391 LKKVDFPVELKIDAKILG---SKKTSQKQRAYRLFAVVYHDGKEASKGHYITDVFHTGYSSWLRY 1452
            :|.:::||:|:|...:|.   ..|..:.||.|||||||||.|..|:.|||.||||..|.:.|||.
 Frog   708 IKNIEYPVDLEISKDLLSPGVKSKIFKGQRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRI 772

  Fly  1453 DDSSVKPVSEKHVLQPHTPRVPYLLYYRRSDTL 1485
            ||.:||.:::..|::....|..|||||||.|.|
 Frog   773 DDQTVKVINQYQVVKQTVERTAYLLYYRRVDLL 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp10	NP_728554.1	UCH	1110..1479	CDD:425685	164/397 (41%)
usp10	NP_001006761.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..170		5/35 (14%)
		UBP12	<423..>642	CDD:227847	90/238 (38%)
		Peptidase_C19	527..800	CDD:239072	124/277 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	561..593		6/32 (19%)