DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dci and CDY2B

DIOPT Version :10

Sequence 1:NP_612065.1 Gene:Dci / 38100 FlyBaseID:FBgn0035169 Length:262 Species:Drosophila melanogaster
Sequence 2:NP_001001722.1 Gene:CDY2B / 203611 HGNCID:23921 Length:541 Species:Homo sapiens


Alignment Length:260 Identity:72/260 - (27%)
Similarity:132/260 - (50%) Gaps:14/260 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 YKELLVEQQ-GKLLVAKFNNPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSGND 69
            |::::|::: |...:.......:||.:|....:||...|.....|:. .:|:|:..|.:|..|.|
Human   284 YRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEMVNALNSAAADDS-KLVLFSAAGSVFCCGLD 347

  Fly    70 -------LSQSSNTDDIDAFFKQSNATFKAMVLSFVNCRKIVLALVNGPAIGIGATIVGLCDVAW 127
                   |....||..::..     .|.|..|.:|:..:|.::..|||||||:||:|:.|||:.|
Human   348 FGYFVRHLRNDRNTASLEMV-----DTIKNFVNTFIQFKKPIVVSVNGPAIGLGASILPLCDLVW 407

  Fly   128 CSETTYFYTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNFVSRIFKASEL 192
            .:|..:|.||:|..|..|:|.||...|.::|::.|:|:|:....|:|:||.....||::|.....
Human   408 ANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKLTAREACAKGLVSQVFLTGTF 472

  Fly   193 ESVIWPKLRQYSELPTNSLLQGKRLVKDGFLENLIKANEAECKQLLQQFQHPEFAQAIIDFASRK 257
            ...:..::::.:......|.:.|.||:......|.:|||.||:.|.:.:...:..::::.:...|
Human   473 TQEVMIQIKELASYNAIVLEECKALVRCNIKLELEQANERECEVLRKIWSSAQGIESMLKYVENK 537

  Fly   258  257
            Human   538  537

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DciNP_612065.1 CaiD 9..258 CDD:440647 71/257 (28%)
CDY2BNP_001001722.1 CD_CDY 5..56 CDD:349284
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 72..104
crotonase-like 287..483 CDD:119339 59/201 (29%)
Blue background indicates that the domain is not in the aligned region.

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