Protein Alignment Dci and ECHS1

DIOPT Version :10

• Sequence 1: NP_612065.1
• Gene: Dci / 38100
• FlyBaseID: FBgn0035169
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 64/273 - (23%)
• Similarity: 117/273 - (42%)
• Gaps: 43/273 - (15%)

  Fly     6 YKELLVEQQGK---LLVAKFNNPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSG 67
            ::.::.|::||   :.:.:.|.||..|.:......|:.:.|....:|..|..:|.||....|.:|
Human    33 FEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAG 97

  Fly    68 NDLSQSSNTDDIDAFFKQSNATFKAMVLSFVNC---------------RKIVLALVNGPAIGIGA 117
            .|:.:..|                   |||.:|               :|.|:|.|||.|.|.|.
Human    98 ADIKEMQN-------------------LSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGC 143

  Fly   118 TIVGLCDVAWCSETTYFYTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNF 182
            .:..:||:.:..|...|..|...:|.:|..|.:..|...:|:|.|.|::|..:.:|||:|.|...
Human   144 ELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGL 208

  Fly   183 VSRIFKASELESVIWPKLRQYSELPTNS---LLQGKRLVKDGFLENLIKANEAECKQLLQQFQHP 244
            ||:|   ..:|:::...::...::.:||   :...|..|...|...|.:.::.|.|.....|...
Human   209 VSKI---CPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATD 270

  Fly   245 EFAQAIIDFASRK 257
            :..:.:..|..::
Human   271 DRKEGMTAFVEKR 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dci	NP_612065.1	CaiD	9..258	CDD:440647	64/270 (24%)
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	64/273 (23%)