Protein Alignment Dci and Cdyl

DIOPT Version :10

• Sequence 1: NP_612065.1
• Gene: Dci / 38100
• FlyBaseID: FBgn0035169
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_034011.1
• Gene: Cdyl / 12593
• MGIID: 1339956
• Length: 593
• Species: Mus musculus
• Alignment Length: 255
• Identity: 73/255 - (28%)
• Similarity: 128/255 - (50%)
• Gaps: 4/255 - (1%)

  Fly     6 YKELLV-EQQGKLLVAKFNNPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSGND 69
            |::::| :|.|...:.......:.|.:|....:|:...|:....|:. .:|:.:.||.:|..|.|
Mouse   336 YRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDS-KLVLLSAVGSVFCCGLD 399

  Fly    70 LSQSSN--TDDIDAFFKQSNATFKAMVLSFVNCRKIVLALVNGPAIGIGATIVGLCDVAWCSETT 132
            ......  |||......:.....:..|.:|:..:|.::..|||||||:||:|:.||||.|.:|..
Mouse   400 FIYFIRRLTDDRKRESTKMADAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKA 464

  Fly   133 YFYTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNFVSRIFKASELESVIW 197
            :|.||:|..|..|:|.|:.|.|.|:|.:.|:|:|.....|:||||.....||::|........:.
Mouse   465 WFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLFSGRKLTAQEACGKGLVSQVFWPGTFTQEVM 529

  Fly   198 PKLRQYSELPTNSLLQGKRLVKDGFLENLIKANEAECKQLLQQFQHPEFAQAIIDFASRK 257
            .::::.:......|.:.|.||:......|.:|||.||:.|.:.:...:...:::.:..||
Mouse   530 VRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRK 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dci	NP_612065.1	CaiD	9..258	CDD:440647	72/252 (29%)
Cdyl	NP_034011.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		Interaction with EZH2. /evidence=ECO:0000250|UniProtKB:Q9Y232	56..304
		CD_CDY	57..106	CDD:349284
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..158
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..223
		crotonase-like	339..535	CDD:119339	59/196 (30%)
		Acetyl-CoA-binding domain. /evidence=ECO:0000255	357..589		67/232 (29%)