Protein Alignment JMJD5 and Hif1an

DIOPT Version :10

• Sequence 1: NP_612063.2
• Gene: JMJD5 / 38097
• FlyBaseID: FBgn0035166
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_795932.2
• Gene: Hif1an / 319594
• MGIID: 2442345
• Length: 349
• Species: Mus musculus
• Alignment Length: 327
• Identity: 85/327 - (25%)
• Similarity: 136/327 - (41%)
• Gaps: 78/327 - (23%)

  Fly   110 EILDEAQLLGCMEDWSELKVALMDYLDKDGAVALNSAPLPTLEPLTRVTSNCDIPQLDAPSLEEF 174
            |..:||:..|...|.|:|:                |...|| .|:.|::      |.| |..||.
Mouse    15 EAREEAEAPGPAWDESQLR----------------SYSFPT-RPIPRLS------QSD-PRAEEL 55

  Fly   175 QTKCFEAGQPTLLLNTIQHWPALHKWLDLNYLLQVAGNRTVPIEIGSNYASDEWSQQLVKIRDFL 239
                .|..:|.:|.:|...:||| || ||.||.:..||....:...|.:....:.::  |:.:|
Mouse    56 ----IENEEPVVLTDTNLVYPAL-KW-DLEYLQENIGNGDFSVYSASTHKFLYYDEK--KMGNF- 111

  Fly   240 SRQFGKEPSKAGQNIEYLAQHELFAQIPAL-----KEDISIPDYCTISNEDTPG---AVDI---- 292
                  :..|...|.|.:..||...::.|:     :|.:    |...:..||.|   .:|.
Mouse   112 ------QNFKPRSNREEIKFHEFVEKLQAIQQRGGEERL----YLQQTLNDTVGRKIVMDFLGFN 166

  Fly   293 ----------KAW---------LGPAGTVSPMHYDPKHNLLCQVFGSKRIILAAPADTDNLYPHD 338
                      :.|         :|..|.|:|.|||.:.|...|:.|.||.||..|...:.|||:.
Mouse   167 WNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGHKRCILFPPDQFECLYPYP 231

  Fly   339 SEFLAN-TARIDAAQLDPETYPLVAKVKFYQLLLQPGDCLYMPPKWWHYVRS---EAPSFSVSFW 399
            .....: .:::|....|.|.:|....|..|:.::.|||.||:|..|||::.|   ...:.:|:||
Mouse   232 VHHPCDRQSQVDFDNPDYERFPNFRNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFW 296

  Fly   400 WE 401
            ::
Mouse   297 YK 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JMJD5	NP_612063.2	Cupin_8	172..401	CDD:463936	70/263 (27%)
Hif1an	NP_795932.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..51		14/59 (24%)
		Interaction with VHL. /evidence=ECO:0000250	2..125		38/148 (26%)
		Cupin_8	53..302	CDD:463936	70/265 (26%)