DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vti1a and Vti1a

DIOPT Version :9

Sequence 1:	NP_612053.1	Gene:	Vti1a / 38085	FlyBaseID:	FBgn0260862	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	XP_038945994.1	Gene:	Vti1a / 65277	RGDID:	621490	Length:	229	Species:	Rattus norvegicus

Alignment Length:	222	Identity:	80/222 - (36%)
Similarity:	138/222 - (62%)	Gaps:	9/222 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EQYEQQYATLIAEITAHIGRLQQQNNNSERHDLCSKIDSSLPEAQELLEQMGLEVRELNPGLRSS 69
            |.|||.:|.|.||||:.|.|:.:...: |:..:.:.::..|.||:||||||.|||||:.|..|..
  Rat     6 EGYEQDFAVLTAEITSKISRVPRLPPD-EKKQMVANVEKQLEEARELLEQMDLEVREIPPQSRGM 69

  Fly    70 FNGKLQVAQAELKRLQAEYRLTKDKQRSQANTFTTLDLGDSYEDVSIS-TDQRQRLLDNSERIER 133
            ::.:::..:.|:.:|:.:::.::.....:.......|.|:|.|:..|. .::|..||||:||:||
  Rat    70 YSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSENQLIKLREERAHLLDNTERLER 134

  Fly   134 TGNRLTEGYRVALET-----EQLGAQVLNDLHHQRETLQGARARLRETNAELGRASRTLNTMMLR 193
            :..||..||::|:||     :|:|.::|.:|.|.||.:|.||.|||||:|.||::||.|..|:.|
  Rat   135 SSRRLEAGYQIAVETGKNSEKQIGQEMLENLSHDRERIQRARERLRETDANLGKSSRILTGMLRR 199

  Fly   194 ALREKVVLYGVGVCFVVAVGVSLYLTF 220
            .::.:::|..:|:  :|.:.:...:||
  Rat   200 IIQNRILLVILGI--IVVITILTAITF 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vti1a	NP_612053.1	V-SNARE	11..89	CDD:282816	27/77 (35%)
Vti1a	NP_612053.1	SNARE_Vti1a	128..189	CDD:277244	32/65 (49%)
Vti1a	XP_038945994.1	V-SNARE	12..89	CDD:398604	27/76 (36%)
Vti1a	XP_038945994.1	SNARE_Vti1a	129..195	CDD:277244	33/70 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337300
Domainoid	1	1.000	75	1.000	Domainoid score	I8884
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39963
Inparanoid	1	1.050	150	1.000	Inparanoid score	I4288
OMA	1	1.010	-	-		QHG54893
OrthoDB	1	1.010	-	-		D1195966at2759
OrthoFinder	1	1.000	-	-		FOG0003233
OrthoInspector	1	1.000	-	-		oto95685
orthoMCL	1	0.900	-	-		OOG6_101479
Panther	1	1.100	-	-	LDO	PTHR21230
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910