Protein Alignment Rev1 and polk

DIOPT Version :10

• Sequence 1: NP_612047.1
• Gene: Rev1 / 38079
• FlyBaseID: FBgn0035150
• Length: 995
• Species: Drosophila melanogaster
• Sequence 2: XP_012822875.2
• Gene: polk / 448219
• XenbaseID: XB-GENE-985768
• Length: 865
• Species: Xenopus tropicalis
• Alignment Length: 934
• Identity: 183/934 - (19%)
• Similarity: 324/934 - (34%)
• Gaps: 305/934 - (32%)

  Fly   175 LKNLQQAVATSPEKEASASESKITNLSTTSNNSTTARTAADPNFLSEFYKNSRLHHIATLGAGF- 238
            :.|.|:| |.:|.|||......:       |::.......|...:::...:      ||.|:.|
 Frog     1 MDNKQEA-ALAPSKEAFQFRMGL-------NDNKAGMEGLDKEKINKIIMD------ATKGSRFY 51

  Fly   239 ----------KQYVCRLRQKHG--TQGFPKRETLK----SLANSHHNCLERYVMHIDMDCFFVSV 287
                      .|.:.:|.|:..  |....|:..::    :|....:..|.|.::|:|||.|:.:|
 Frog    52 DNELKKDQQVNQRIEKLMQQKSQLTDQQIKKAQIQVDRLALELERNRDLSRIIVHVDMDAFYAAV 116

  Fly   288 GLRTRPELRGLPIAVTHSKGGNAATDVPVHPQADRKAELELFAQRFEHHFHDGDKAEKVRSGFDK 352
            .:|..|||:..|:||    |.|
 Frog   117 EMRDSPELKDKPMAV----GSN------------------------------------------- 134

  Fly   353 KMSLSEIASCSYEAREKGIRNGM--FVGQALKLCPELKTIPYDFEGYKEVAFTLYDTVAQYTLNI 415
                |.:::.:|.||..|:|..|  |:  |.||||.||.:|.:|:.|:.|:..:.:.:|||..|.
 Frog   135 ----SMLSTSNYLARRFGVRAAMPGFI--AKKLCPTLKIVPPNFDKYRAVSSEVREILAQYDPNF 193

  Fly   416 EAVSCDEMFVELTDLAHE-------------------------------------LNVDVMAFVS 443
            ..:|.||.::::||...|                                     |..|..:||:
 Frog   194 LPMSLDEAYLDITDHLSERLAWPEDKRTFMIRTNNSGGNKPLPGKQEQVECTSPVLFEDSPSFVA 258

  Fly   444 -----------------------------------HLRQEVYSKTGCPCSAGVAGNKLLARMATK 473
                                               .:|..:..||....|||:|.|.:||::.:.
 Frog   259 DQNFSQPGLGTTEENRKPSLENVVVFGTSVEEAVKEMRFRIEQKTTLTASAGIAPNMMLAKVCSD 323

  Fly   474 EAKPNGQF-LLDSSNDILAYMAPMSLDLLPGVGSSISHKLKQAGLNNCGDV-QNTTLEKMEKVLG 536
            :.|||||: :.:....|..::..:.:..:||:|......||..|:..|.|: |...|  :..:..
 Frog   324 KNKPNGQYRIFNDKQAIKDFIKDLPIRKVPGIGKVTEKMLKALGIITCTDLYQQRAL--LSLLFS 386

  Fly   537 KKLGQNLFQNCRGIDDRPLAYEQIRKTVSAEMNFGIRFTNSVE----CEQFLCQLSEEVTK---- 593
            :...||......|:....:..:..||::|.|..|. ..::|.|    |::....|::::.|
 Frog   387 ETSWQNFVHISLGLGSTHVERDGERKSMSTERTFS-EISSSEEQYGLCQELCRDLAQDLQKEGLK 450

  Fly   594 -RLVEIRRKARSINLKIMVRAAEAPVETSKYMGHGVCDIINKSSLIKYATDDVNVITTVVLDLMK 657
             :.|.|:.|    |:|..||.....|.::         :..:..:...|.:    |....:||
 Frog   451 GKTVTIKLK----NVKFEVRTRALTVGST---------VSTEEEIFAVAKE----ILKAEIDL-- 496

  Fly   658 DADIPPDELRGLGIHLTRLEDANEVRKENNIKEMFGKMSEMRKDKPIPQGAVGDKSIGDDKVN-- 720
             |...|..||.:|:.::..  ..|..|:::.|.:.|   .:...||....::|.    .||.|
 Frog   497 -ASPEPLRLRLMGVRVSGF--LTEEEKKHHQKSITG---FLHVSKPGSSSSLGQ----SDKANPS 551

  Fly   721 -------KPLVFENKPKPR-----EPRNVLSMLTAAAVSRKSVTEDRS-----QRGTSKP-ITRP 767
                   :...|..|...|     |...|.|....:..:..|.:|.::     :..:.|| .|.|
 Frog   552 ALATGPQRQSFFNQKRAAREHMVQEKHAVCSGFVKSEDATISDSEGKTETLDLENVSQKPEFTCP 616

  Fly   768 LSLVPKLDEDVLAQLPEDIRLEVIANREEHL--CIAEYDGYRSPQYPTLRSPPLLNPYVTTN--- 827
            :..:.:.|.|             :|:..:|:  |::     |||....|.||......:..|
 Frog   617 ICFLKESDWD-------------LASFNKHIDKCLS-----RSPISSELESPYKEGAVMMRNEVG 663

  Fly   828 ----------------------VSPLKATDLK--PSTSRAAVARLQKRKERKEQEHYIRSDQIVA 868
                                  ..||.|.|..  .:|....|..::......:..|.|.:..|..
 Frog   664 DMEIQCEGIHNADVCAKKQIGHTRPLDAFDDSGINNTETTTVEDVEMNVNMDQSHHSIIATSIKN 728

  Fly   869 DYIDDLPDFVNPHILKLISHPVEMPELLMGDNYKDLLNDWVSREEVPKPNDVDLILKQVSRMIKN 933
            :|             |:.|.|:....|:   ..|..|:|    .||..|:..
 Frog   729 EY-------------KMASEPIYAENLI---ECKVNLSD----TEVAHPSSA------------- 760

  Fly   934 DQLDHVCDVMKYWCRIINMKRSSS 957
                ..|:...:.|.:.|:::.::
 Frog   761 ----APCEEQSFICPVCNIRQDTA 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rev1	NP_612047.1	BRCT_Rev1	39..121	CDD:349351
		PolY_Rev1	218..676	CDD:176455	116/559 (21%)
		Rev1_C	890..985	CDD:213388	10/68 (15%)
polk	XP_012822875.2	PolY_Pol_IV_kappa	105..514	CDD:176459	104/484 (21%)
		ZnF_Rad18	768..793	CDD:128973	2/13 (15%)