Protein Alignment Rev1 and eso1

DIOPT Version :10

• Sequence 1: NP_612047.1
• Gene: Rev1 / 38079
• FlyBaseID: FBgn0035150
• Length: 995
• Species: Drosophila melanogaster
• Sequence 2: NP_596778.1
• Gene: eso1 / 2539666
• PomBaseID: SPBC16A3.11
• Length: 872
• Species: Schizosaccharomyces pombe
• Alignment Length: 910
• Identity: 165/910 - (18%)
• Similarity: 303/910 - (33%)
• Gaps: 336/910 - (36%)

  Fly   248 KHGTQGFPKRETLKSLANSHHNCLERYVMHIDMDCFFVSVGLRTRPELRGLPIAVTHSKGGNAAT 312
            |.|||..|.                |.|.|||.|.|:..|
pombe    18 KAGTQNSPL----------------RVVAHIDQDAFYAQV------------------------- 41

  Fly   313 DVPVHPQADRKAELELFAQRFEHHFHDGDKAEKVRSGFDKKMSLS-----EIASCSYEAREKGIR 372
                                           |.||.|.|..:.|:     .:.:.:|.||...|.
pombe    42 -------------------------------ESVRLGLDHSVPLAVQQWQGLIAVNYAARAANIS 75

  Fly   373 NGMFVGQALKLCPELKTI----------------------------PYDFEGYKEVAFTLYDTVA 409
            ....|.:|.|.||||.|.                            ||..|..|     :.:.:.
pombe    76 RHETVTEAKKKCPELCTAHVKTWKAGESEAKYHENPNPNYYKTCLDPYRHESVK-----ILNIIK 135

  Fly   410 QYTLNIEAVSCDEMFVELT-DL--------------AHELNV----------------------- 436
            ::...::..|.||.|:||| |:              :.:.||
pombe   136 KHAPVVKKASIDECFIELTSDVKRIVLEEYPYLKIPSEDSNVALPQAPVLLWPAEFGMVIEEEVV 200

  Fly   437 ------------DVMAF-----VSHLRQEVYSKTGCPCSAGVAGNKLLARMATKEAKPNGQFLLD 484
                        ||..|     |..:|.::|.:....|||||:.|.:|:::.:...|||.|.:|
pombe   201 DRTKEDYERDWDDVFLFYAAKIVKEIRDDIYLQLKYTCSAGVSFNPMLSKLVSSRNKPNKQTIL- 264

  Fly   485 SSNDILAYMAPMSLDLLPGVGSSISHK-LKQAGLNNCGDVQNTTLEKMEKVLGKKLGQNLFQNCR 548
            :.|.|..|:..:.:..:..:|.....: :...|.::..||.|.:::.:...||:..|..::..|.
pombe   265 TKNAIQDYLVSLKITDIRMLGGKFGEEIINLLGTDSIKDVWNMSMDFLIDKLGQTNGPLVWNLCH 329

  Fly   549 GIDDRPLAYE-QIRKTVSAEMNFGIRFTNSVE-CEQFLCQLSEEVTKRLVEIR--RKARSINLKI 609
            |||:..:..: ||:..:||: ||..:...|.| ...:....:.::..|.:|:.  |:.::|.|.:
pombe   330 GIDNTEITTQVQIKSMLSAK-NFSQQKVKSEEDAINWFQVFASDLRSRFLELEGMRRPKTICLTV 393

  Fly   610 M------VRAAEAPVE-----------TSKYMGH-----GVCDIINKS----------------- 635
            :      .|:::.|:.           |||.:..     .|..|.|.|
pombe   394 VSRFLRKSRSSQIPMNVDISTQFIVEATSKLLRQLQQEFDVYPISNLSISFQNIIEVDRNSRGIE 458

  Fly   636 SLIKYATDDVNVITTVVLDLMKDADIPPDELRGLGIHLTRLEDANEVRKENNIKEMFGKMSEMRK 700
            ..:|.:.|::.:.|:|           ...:.|      |.:..||..:|||..|:..: .:::.
pombe   459 GFLKKSNDEIYMSTSV-----------SPSIEG------RAKLLNENMRENNSFELSSE-KDIKS 505

  Fly   701 DKPIPQGAVGDKSIGDDKVNKPLVFENKPKPREPRNVLSMLTAAAVSRKSVTEDRSQRGTSKPIT 765
            .|.:.:|                         :.:.:..||...|||:.  ||:.:
pombe   506 PKRLKRG-------------------------KGKGIFDMLQQTAVSKP--TENSA--------- 534

  Fly   766 RPLSLVPKLDEDVLAQLPEDIRLEV-IANREEH------LCIAEYDGYRSPQYPTLRSPPLLNPY 823
                     ||....   |:...:: ::.|.||      |.|:..:.|.:...|:...|..:.|
pombe   535 ---------DETYTC---EECEQKITLSERNEHEDYHIALSISRKERYNNLVPPSHDKPKQVKP- 586

  Fly   824 VTTNVSPLKATDLKPSTSRAAVARLQKRKERKEQEHYI-RSDQIVADYIDDLPDFVNPHILKLIS 887
                    |....|..:...|....:...:|...:.:: ....:..::....|        |.||
pombe   587 --------KTYGRKTGSKHYAPLSDETNNKRAFLDAFLGNGGNLTPNWKKQTP--------KAIS 635

  Fly   888 HPVE-MPELLMGDNYKDLLNDWVSREEVP----KPNDVDLIL--KQVSRMIKNDQLDHVCDVMKY 945
            :..: |.:|     :.||.|..|:..|..    ..::.|::|  :..||::....:...|..:..
pombe   636 NSSDNMTQL-----HLDLANSTVTCSECSMEYNSTSEEDILLHSRFHSRVLGGVTVSFQCSPIYR 695

  Fly   946 WCRIINMKRSSSCCWH-------VAYKHIEES---IQNQM-------LTIEGY-SLLFIEYIRCI 992
                :|...||.|.:.       :..:..||:   :.|::       :.::.| :.|||...:|:
pombe   696 ----VNYGLSSDCIYSINSESSLIDQRKAEEALSFVNNELSSEPIETIGVDKYTTFLFISDKKCV 756

  Fly   993  992
            pombe   757  756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rev1	NP_612047.1	BRCT_Rev1	39..121	CDD:349351
		PolY_Rev1	218..676	CDD:176455	105/559 (19%)
		Rev1_C	890..985	CDD:213388	20/119 (17%)
eso1	NP_596778.1	PolY_Pol_eta	30..446	CDD:176456	93/478 (19%)
		zf_UBZ	536..567	CDD:465769	7/33 (21%)
		zf-C2H2_3	643..679	CDD:464013	8/40 (20%)
		Acetyltransf_13	797..853	CDD:464015