Protein Alignment Reg-2 and HDHD3

DIOPT Version :10

• Sequence 1: NP_612043.1
• Gene: Reg-2 / 38075
• FlyBaseID: FBgn0016715
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_112496.1
• Gene: HDHD3 / 81932
• HGNCID: 28171
• Length: 251
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 70/249 - (28%)
• Similarity: 124/249 - (49%)
• Gaps: 28/249 - (11%)

  Fly     6 RFRLITFDVTNTLLQFRTTPGKQYGEIGALFGARCDNNELAKNFKANWYKMNRDYPNFGRDTNPQ 70
            :.||:|:||.:|||:.|...|:.|.......|...:.:.|.:.|:..:...:..:||:|  .:..
Human     6 QIRLLTWDVKDTLLRLRHPLGEAYATKARAHGLEVEPSALEQGFRQAYRAQSHSFPNYG--LSHG 68

  Fly    71 MEWQQWWRKLIAGTF-------AESGAAIPDEKLHNFSNHLIELYKTSICWQPCNGSVELLQQLR 128
            :..:|||..::..||       |::.|.|.::...:||:        ...||..:|:.:.|
Human    69 LTSRQWWLDVVLQTFHLAGVQDAQAVAPIAEQLYKDFSH--------PCTWQVLDGAEDTL---- 121

  Fly   129 KELKPEKCKLGVIANFDPRLPTLLQNTKLDQYLDFAINSYEVQAEKPDPQIFQKAMEKSGLKNLK 193
            :|.:....:|.||:|||.||..:|....|.::.||.:.|......||||:|||:|:.   |.:::
Human   122 RECRTRGLRLAVISNFDRRLEGILGGLGLREHFDFVLTSEAAGWPKPDPRIFQEALR---LAHME 183

  Fly   194 PEECLHIGDGPTTDYLAAKELGWHSAL-VHEKSYAYLVKKYGEDIDRDHVFPSL 246
            |....|:||....||...:.:|.||.| |..::...:|:   :.:.::|:.|||
Human   184 PVVAAHVGDNYLCDYQGPRAVGMHSFLVVGPQALDPVVR---DSVPKEHILPSL 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reg-2	NP_612043.1	DREG-2	8..220	CDD:274056	63/218 (29%)
HDHD3	NP_112496.1	DREG-2	8..210	CDD:274056	63/218 (29%)