Protein Alignment Hipk and Prp4k

DIOPT Version :10

• Sequence 1: NP_001369036.1
• Gene: Hipk / 38070
• FlyBaseID: FBgn0035142
• Length: 1409
• Species: Drosophila melanogaster
• Sequence 2: NP_001286884.1
• Gene: Prp4k / 38032
• FlyBaseID: FBgn0027587
• Length: 912
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 148/548 - (27%)
• Similarity: 246/548 - (44%)
• Gaps: 80/548 - (14%)

  Fly    19 GGGGSGFCSGLGAG--------LSV---RATSFYGDQTVTATTDGTRHQEQQQ-QQLQQQQQQHI 71
            |||..|..||...|        ||.   :......|:.|....|.....:::: .:|::::::.:
  Fly   393 GGGRVGARSGTDNGDRDRYKGSLSEGQNKLDKESSDEEVNVNIDILEEDDEERIIELRRKKREEL 457

  Fly    72 LRQ---------PATSASTSSVAAA-ATSKRKRQTDCDCGCVDSYNS--SHGPPVQQDSSAAAGA 124
            |::         |..|.|..|.:.: .:|:|:|........:...|.  |..|..::|...:...
  Fly   458 LKKLGTGQESPAPHNSVSYESRSTSQGSSQRERPLRTPSPTMPCPNPLISEIPKDREDMDNSTSQ 522

  Fly   125 GSVGSKAG-------SGPGPDGIGPISSLKTAHTKVATSGGHANTQPPSKRSSSGADGDYQLVQH 182
            .:..:|..       :....|....:|...:.:|.|.....|.|  |....:...|:|.|::...
  Fly   523 KTCSAKEKRNEWDMFADQDVDSNFDVSRKISPNTIVQNKHQHEN--PALTDNWDDAEGYYRVRIG 585

  Fly   183 EVLYSLSAEYEVLEFLGRGTFGQVVKCWKRGTSEI-----VAIKILKNHPSYARQGQIEVSILSR 242
            ||   |...|.|..:.|:|.|..||    ||..:.     |||||::|:....:.|..|:.||.:
  Fly   586 EV---LDNRYLVNGYTGQGVFSNVV----RGRDQARGQANVAIKIIRNNEIMHKTGLRELEILKK 643

  Fly   243 LSQ-ENADEFNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQ-NKFSPLPLKYIRPILEQVLTAL 305
            |:. :..|.|:.:|.:..|.||.|.|:|||.|..||.:.||: .|...|.:|.:|...:|:..||
  Fly   644 LNDADPEDRFHCLRLYRHFFHKQHLCMVFEPLAMNLREVLKKYGKNVGLHIKAVRSYTQQLFLAL 708

  Fly   306 LKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLP 370
            ..||:.|::|||:||:||::.:   ....:|:.||||||.:|......||.||:||:||||||:|
  Fly   709 KLLKKTGILHADIKPDNILVNE---NNLILKLCDFGSASAISDNEITPYLVSRFYRSPEIILGIP 770

  Fly   371 FCEAIDMWSLGCVVAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSA-------SKTSKFF 428
            :...||.||.||.:.||:.|..|:.|.|....:::....:|.....::...       .::..|.
  Fly   771 YDYGIDTWSAGCTIYELYTGKILFSGKSNNQMLKFFMDVKGKIPNRIIRKGQFREQHFDQSCNFL 835

  Fly   429 YRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDRR-- 491
            |.::|        |.||..:.......|.:|             ::..:|...|.|.:...|:
  Fly   836 YHEID--------KLTEREKIVVMPVVKPSR-------------SLQQELIADQNLPDDQHRKVT 879

  Fly   492 EFIDLLKRMLTIDQERRLTPAEALNHSF 519
            :..|||:.|..:|..:|::..:||.|.|
  Fly   880 QLKDLLENMFALDPAKRISLNQALVHPF 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hipk	NP_001369036.1	STKc_HIPK	192..520	CDD:271113	109/344 (32%)
		PHA03378	<1080..1327	CDD:223065
Prp4k	NP_001286884.1	STKc_PRP4	591..908	CDD:271037	109/345 (32%)