Protein Alignment Hipk and C36B7.2

DIOPT Version :10

• Sequence 1: NP_001369036.1
• Gene: Hipk / 38070
• FlyBaseID: FBgn0035142
• Length: 1409
• Species: Drosophila melanogaster
• Sequence 2: NP_509198.2
• Gene: C36B7.2 / 183254
• WormBaseID: WBGene00016465
• Length: 446
• Species: Caenorhabditis elegans
• Alignment Length: 354
• Identity: 87/354 - (24%)
• Similarity: 159/354 - (44%)
• Gaps: 44/354 - (12%)

  Fly   177 YQLVQHEVLYSLSAEYEVLEFLGRGTFGQVVKCWKRGTSEIVAIKIL-KNHPSYARQGQIEVSIL 240
            |::.:.|   .:...|.:.:.:|:|.:|.|.:.....|.:.|||::: |..|...|    |..::
 Worm    98 YKMKKDE---HIGYRYTIDKVIGQGCYGVVGEATDGKTKQKVAIRMVSKLAPRIYR----ETEMI 155

  Fly   241 SRLSQENADE-FNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILEQVLTA 304
            ..:|..:.|. |:.||..:....:....:|.::.:.::..::|::..:.:.|:.:..:..::|..
 Worm   156 MYISSIDPDHTFDCVRMLDYNVFRGFHYVVTDLFDTSVKKYIKEHHPNGIALENVAAMGRKILKG 220

  Fly   305 LLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGL 369
            |:.|.:..::|.|||||||||  .:..|..||:.|||.:........:...||.:|||||..:..
 Worm   221 LVFLHEHNIVHGDLKPENIML--NLANPNDVKLGDFGLSRFAKPYHDHVQCQSMFYRAPEAFVRG 283

  Fly   370 PFCEAIDMWSLGCVVAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVDS 434
            .:..|.||||.||.|||:..|.....|.:..||...:.:...:|.....::       ||.:.
 Worm   284 RYNGATDMWSFGCTVAEMVSGKIFLAGDNCDDQFYLMQEVINIPPPVFFDT-------FYTNY-- 339

  Fly   435 TYPFWRLKTTEEHEAETN---------TKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDR 490
             |.|..||...:|...|:         ||:.:.||             :|.....|.... ||::
 Worm   340 -YFFSTLKEAPKHIVITDHGPIVSFIYTKAADHRK-------------IPGATPIGSFFT-KTEQ 389

  Fly   491 REFIDLLKRMLTIDQERRLTPAEALNHSF 519
            :.|.:.:.::.......|:|..:||:|.|
 Worm   390 KPFNNFILKVFKWMPASRITAKQALDHPF 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hipk	NP_001369036.1	STKc_HIPK	192..520	CDD:271113	85/339 (25%)
		PHA03378	<1080..1327	CDD:223065
C36B7.2	NP_509198.2	Protein Kinases, catalytic domain	98..419	CDD:473864	87/354 (25%)