Protein Alignment CG1231 and ZNF385D

DIOPT Version :10

• Sequence 1: NP_612032.1
• Gene: CG1231 / 38060
• FlyBaseID: FBgn0035134
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: XP_016862680.1
• Gene: ZNF385D / 79750
• HGNCID: 26191
• Length: 515
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 89/428 - (20%)
• Similarity: 143/428 - (33%)
• Gaps: 144/428 - (33%)

  Fly    34 PDAEISTSNRLVAP--GKRTDKKDNGSIRTNMKRKAKCMEEDSLKANGDLALFPGRDESYPEELN 96
            |....:.|.|:.:.  |:|  :|..|:.:....|...|:.:...:|.    |.|...|..||...
Human     4 PGRRAAASRRMKSSVGGRR--EKLLGAPKAQPSRDFTCVHDGESEAE----LIPDDFEEKPEREK 62

  Fly    97 RLIGPLNCQLCKVQMTSRKRARDHYESKAHD---RHISAWLAKNYTEVGLEAPPVKRLAKQGPTG 158
            :......|.:|.:|:.|..:|:.||..|:|.   :.:|....||......::|.:..|.:  |..
Human    63 KHTNFTLCNVCNIQLNSAAQAQIHYNGKSHQKRLKQLSNGTLKNDNGGTCQSPALPALVR--PPA 125

  Fly   159 P----------------------NAF------------------------------HCELCNLDL 171
            |                      |.|                              .|.:|.|..
Human   126 PPLQPSLDIKPFLPFPLDTAAAVNLFPNFNAMDPIQKAVINHTFGVPLPHRRKQIISCNICQLRF 190

  Fly   172 TSSMHARQHYLGRKH----KRVE-------------------------------------QGVAK 195
            .|...|..||.|.||    |.:|                                     :|..|
Human   191 NSDSQAAAHYKGTKHAKKLKALEAMKNKQKSVTAKDSAKTTFTSITTNTINTSSDKTGGKKGAMK 255

  Fly   196 PSG--ARHC--DTSVGRYGIGSL----FRKPESLTKD-------SPTDVLISENSVIKSDDNERT 245
            |.|  ...|  |.:.|...|.:.    .||...:|.:       |||..  :.||...|.:.|..
Human   256 PCGLFLPFCTRDGTAGTPAISTTTTVEIRKSSVMTTEITSKVEKSPTTA--TGNSSCPSTETEEE 318

  Fly   246 -------CHLCKIVVTSAAQMQAHLAGARHQKNWRTSRQDQNHS-------EAPIPETEKLDAAE 296
                   |.|||:.|.||:|::||.:|.:|    :|..:.:|.|       .|.:.....::...
Human   319 KAKRLLYCSLCKVAVNSASQLEAHNSGTKH----KTMLEARNGSGTIKAFPRAGVKGKGPVNKGN 379

  Fly   297 LALYRTPMGQYYCQPCNMMMNHESTLQQHFIGKKHLKR 334
            ..|...   .::|:.|::.:|.|:.|:||...::|..|
Human   380 TGLQNK---TFHCEICDVHVNSETQLKQHISSRRHKDR 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1231	NP_612032.1	C2H2 Zn finger	104..163	CDD:275371	18/113 (16%)
		zf-met	104..126	CDD:463736	8/21 (38%)
		zf-met	162..186	CDD:463736	9/53 (17%)
		C2H2 Zn finger	164..186	CDD:275371	8/21 (38%)
		zf-met	245..268	CDD:463736	11/29 (38%)
		ZnF_U1	304..336	CDD:197732	9/31 (29%)
ZNF385D	XP_016862680.1	C2H2 Zn finger	70..92	CDD:275371	8/21 (38%)
		zf-met	70..92	CDD:463736	8/21 (38%)
		C2H2 Zn finger	183..205	CDD:275371	8/21 (38%)
		zf-met	183..205	CDD:463736	8/21 (38%)
		zf-met	324..348	CDD:463736	11/23 (48%)
		C2H2 Zn finger	326..348	CDD:275371	11/21 (52%)
		zf-met	387..411	CDD:463736	7/23 (30%)
		C2H2 Zn finger	389..411	CDD:275371	7/21 (33%)