DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1231 and Zfp385a

DIOPT Version :9

Sequence 1:	NP_612032.1	Gene:	CG1231 / 38060	FlyBaseID:	FBgn0035134	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	XP_038935827.1	Gene:	Zfp385a / 685474	RGDID:	1593784	Length:	423	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	61/275 - (22%)
Similarity:	93/275 - (33%)	Gaps:	96/275 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 GPL--------NCQLCKVQMTSRKRARDHYESKAHDRHISAWLAKNYTEVGLEA-------PPVK 149
            |||        :|.:|:::..|:.:|..||:...|.|.:.          |:||       |.|:
  Rat   101 GPLLKTKRPVISCNVCQIRFNSQSQAEAHYKGNRHARRVK----------GIEAAKTRGREPSVR 155

  Fly   150 RLAKQGPTGPNAFHCELCNLDLTSSMHARQHYLGRKHKRVEQGVAKPSGARHCDTSVG-RYGIGS 213
            ......|.|.                                  ..|||.......|. ..|:|.
  Rat   156 ESGDPAPAGS----------------------------------TPPSGDGVAPRPVSMENGLGP 186

  Fly   214 LFRKPESLT-KDSPTDVLISENSVIK---------------SDDNERT-----CHLCKIVVTSAA 257
            ....||... ..||..|..|...|.|               .::.|:.     |.|||:.|.|.:
  Rat   187 APGSPEKQPGSPSPPSVPESGQGVTKGEGGTSVPASLPGGSKEEEEKAKRLLYCALCKVAVNSLS 251

  Fly   258 QMQAHLAGARHQKNWRTSRQDQNHSEA------PIPETEKLDAAELALYRTPMGQYYCQPCNMMM 316
            |::||..|.:| |....:|......:|      |.|...:..|.:    ||    ::|:.||:.:
  Rat   252 QLEAHNKGTKH-KTILEARSGLGPIKAYPRLGPPTPGEPEAPAQD----RT----FHCEICNVKV 307

  Fly   317 NHESTLQQHFIGKKH 331
            |.|..|:||...::|
  Rat   308 NSEVQLKQHISSRRH 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1231	NP_612032.1	C2H2 Zn finger	104..163	CDD:275371	15/65 (23%)
		zf-met	104..126	CDD:289631	6/21 (29%)
		zf-met	163..186	CDD:289631	0/22 (0%)
		C2H2 Zn finger	164..186	CDD:275371	0/21 (0%)
		UFD2	255..>338	CDD:227443	23/83 (28%)
		ZnF_U1	304..336	CDD:197732	9/28 (32%)
Zfp385a	XP_038935827.1	C2H2 Zn finger	113..135	CDD:275371	6/21 (29%)
		zf-met	113..135	CDD:403930	6/21 (29%)
		zf-met	238..262	CDD:403930	10/23 (43%)
		C2H2 Zn finger	240..262	CDD:275371	10/21 (48%)
		zf-met	298..322	CDD:403930	8/23 (35%)
		C2H2 Zn finger	300..322	CDD:275371	8/21 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342054
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.800