DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1231 and ZMAT3

DIOPT Version :9

Sequence 1:	NP_612032.1	Gene:	CG1231 / 38060	FlyBaseID:	FBgn0035134	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001362753.1	Gene:	ZMAT3 / 64393	HGNCID:	29983	Length:	289	Species:	Homo sapiens

Alignment Length:	306	Identity:	71/306 - (23%)
Similarity:	112/306 - (36%)	Gaps:	103/306 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 KANGDLALFP----GRDESYP----EELNR----------LIGPLNCQLCKVQMTSRKRARDHYE 122
            ::.|.|.|.|    |::.|.|    |||::          |..||.|:||.|.:.|.::|:.||:
Human    26 RSTGTLQLPPQKPFGQEASLPLAGEEELSKGGEQDCALEELCKPLYCKLCNVTLNSAQQAQAHYQ 90

  Fly   123 SKAHDRHISAWLAKNYTEVGLEAPPVKRLA---------------KQGPTGPNA--------FHC 164
            .|.|.:.:..:.|.|      ..||..|::               :.|...|..        .:|
Human    91 GKNHGKKLRNYYAAN------SCPPPARMSNVVEPAATPVVPVPPQMGSFKPGGRVILATENDYC 149

  Fly   165 ELCNLDLTSSMHARQHYLGRKH-KRVEQGVAKPSGARHCDTSVGRYGIGSLFRKPESLTKDSPTD 228
            :||:...:|...|:.||.|:.| ||:....|:.:.
Human   150 KLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNS------------------------------ 184

  Fly   229 VLISENSVIKSDDNERTCHLCKIVVTSAAQMQAHLAG--ARHQKNWRTSRQDQNHSEAPI--PET 289
              .||:|.:                   .|.:|...|  .:...|.|.....||:|..|.  |.:
Human   185 --FSESSEL-------------------GQRRARKEGNEFKMMPNRRNMYTVQNNSAGPYFNPRS 228

  Fly   290 EKLDAAELALYRTPMGQYYCQPCNMMMNHESTLQQHFIGKKHLKRV 335
            .:....:||:..||.||:||..||:....|...:||...|:|..:|
Human   229 RQRIPRDLAMCVTPSGQFYCSMCNVGAGEEMEFRQHLESKQHKSKV 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1231	NP_612032.1	C2H2 Zn finger	104..163	CDD:275371	17/81 (21%)
		zf-met	104..126	CDD:289631	9/21 (43%)
		zf-met	163..186	CDD:289631	8/22 (36%)
		C2H2 Zn finger	164..186	CDD:275371	8/21 (38%)
		UFD2	255..>338	CDD:227443	26/85 (31%)
		ZnF_U1	304..336	CDD:197732	12/32 (38%)
ZMAT3	NP_001362753.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42		5/15 (33%)
		ZnF_U1	67..101	CDD:197732	12/33 (36%)
		C2H2 Zn finger	72..94	CDD:275371	9/21 (43%)
		ZnF_U1	144..177	CDD:197732	11/32 (34%)
		C2H2 Zn finger	149..171	CDD:275371	8/21 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	180..201		6/71 (8%)
		ZnF_U1	243..277	CDD:197732	12/32 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148186
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1565630at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40727
orthoMCL	1	0.900	-	-		OOG6_111409
Panther	1	1.100	-	-	LDO	PTHR46786
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5774
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.880