DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1231 and znf346

DIOPT Version :9

Sequence 1:	NP_612032.1	Gene:	CG1231 / 38060	FlyBaseID:	FBgn0035134	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001075218.1	Gene:	znf346 / 560756	ZFINID:	ZDB-GENE-070209-152	Length:	301	Species:	Danio rerio

Alignment Length:	287	Identity:	65/287 - (22%)
Similarity:	105/287 - (36%)	Gaps:	73/287 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 NGDLALFPGRDESYPEELNRLI-------GPLNCQLCKVQMTSRKRARDHYESKAHDRHISAWLA 135
            |||....|    |...|:||:|       ....|::|...:.|..:...||:||.|...:..:::
Zfish    28 NGDFPYLP----SGAAEVNRMIKENSDLFSDSQCKVCSAVLISESQKLAHYQSKKHASKVRRYMS 88

  Fly   136 KNYTEVGLEAPPVKRLAKQGPTGPNAFH------CELCNLDLTSSMHARQHYLGRKHKRVEQGVA 194
            .:    |.|.|..||....|....|...      |.:||:..:|.:.|:.||.|:.|.:
Zfish    89 IH----GSEEPIAKRFKPSGDDQSNVDEKDKYKACSVCNMTFSSPVVAQSHYQGKVHSK------ 143

  Fly   195 KPSGARHCDTSVGRYGIGS---LFRKPESLTK-----DSPTDVLISENSVIKSDDNERTCHLCKI 251
                      ::....|||   ...:||:..|     ..|.:           .|..|.|.:|:.
Zfish   144 ----------NLRMQSIGSQTPALPQPEAQAKKDDGMQGPAE-----------QDPNRFCSICQA 187

  Fly   252 VVTSAAQMQAHLAGARHQKNWRTSRQDQNHSEAPIPETEKLDAAELALYRTPMGQYYCQPCNMMM 316
            ...:....|.|.:|.:|:|:....:..:....:..|.:            |..| |.|..||:.:
Zfish   188 SFNNPLMAQQHYSGKKHKKHMNKQKLMETFGPSTAPAS------------TVKG-YPCTVCNIEL 239

  Fly   317 NHESTLQQHFIGKKHLKRVKNLSQTEK 343
            |.....|.|..|.||    ||.::.:|
Zfish   240 NSVEQYQAHISGSKH----KNHAKPKK 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1231	NP_612032.1	C2H2 Zn finger	104..163	CDD:275371	15/58 (26%)
		zf-met	104..126	CDD:289631	7/21 (33%)
		zf-met	163..186	CDD:289631	8/28 (29%)
		C2H2 Zn finger	164..186	CDD:275371	8/21 (38%)
		UFD2	255..>338	CDD:227443	19/82 (23%)
		ZnF_U1	304..336	CDD:197732	11/31 (35%)
znf346	NP_001075218.1	ZnF_U1	57..86	CDD:197732	8/28 (29%)
		C2H2 Zn finger	57..79	CDD:275371	7/21 (33%)
		ZnF_U1	119..148	CDD:197732	9/44 (20%)
		C2H2 Zn finger	119..141	CDD:275371	8/21 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	151..177		6/36 (17%)
		ZnF_U1	177..211	CDD:197732	9/33 (27%)
		C2H2 Zn finger	182..204	CDD:275371	5/21 (24%)
		C2H2 Zn finger	232..254	CDD:275371	7/21 (33%)
		zf-met	232..254	CDD:289631	7/21 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	250..283		6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582124
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I5301
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1565630at2759
OrthoFinder	1	1.000	-	-		FOG0001854
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.900