DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atac3 and DBP10

DIOPT Version :9

Sequence 1:	NP_001246531.1	Gene:	Atac3 / 38055	FlyBaseID:	FBgn0052343	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_010253.2	Gene:	DBP10 / 851530	SGDID:	S000002189	Length:	995	Species:	Saccharomyces cerevisiae

Alignment Length:	493	Identity:	101/493 - (20%)
Similarity:	157/493 - (31%)	Gaps:	149/493 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 DLGKQLLQCARDSDVAGVKAALAH---------GAP---------FASDWLGMSALHFAAMNNQL 99
            ||.|.|:....|..:|...|..|.         .:|         .:|.|...:|  |...|.:.
Yeast   608 DLYKNLMSSNFDLQLAKKTAMKAEKLYYRTRTSASPESLKRSKEIISSGWDAQNA--FFGKNEEK 670

  Fly   100 EICEIL--LQGGINMDGKTKVDRTPLHLACYYGHERIVSLLLALKCSVNSRDML---RMTPLHWA 159
            |..:.|  ||...|.:...:..|.|......:...|...|....:.:...|::|   ||..|..:
Yeast   671 EKLDFLAKLQNRRNKETVFEFTRNPDDEMAVFMKRRRKQLAPIQRKATERRELLEKERMAGLSHS 735

  Fly   160 VEKKHKGIVRLLLKCQADVTLVSKFGKTPIGLAVYTEQADVLAELEAARQAQASKKLHEESEQQA 224
            :|               |..|....|:|.     ||...|.|.|.|.|.|      |.|..|.:.
Yeast   736 IE---------------DEILKGDDGETG-----YTVSEDALKEFEDADQ------LLEAQENEN 774

  Fly   225 HKTKKETNEAVSSIMDEPEVIK------TVDDKEMSVEERMDVLENMRGHANVLRNTALYILKTH 283
            .|.||.     .|..|....:.      .:.||::.:         ..|.||.....| |.|.:.
Yeast   775 KKKKKP-----KSFKDPTFFLSHYAPAGDIQDKQLQI---------TNGFANDAAQAA-YDLNSD 824

  Fly   284 EIADMVQDND-------DEDSKEMLNTALQNGRQLVLSEGGRMLLHETKSGISGKQSTNGNARPS 341
               |.||.:.       |:..|:.:||...:.::.::.|.|:.:....:||.....|...|.:|
Yeast   825 ---DKVQVHKQTATVKWDKKRKKYVNTQGIDNKKYIIGESGQKIAASFRSGRFDDWSKARNLKP- 885

  Fly   342 VAALRTNVNNSHPKIRMNVLKQKDLPSPAGVAKNKNIRIISLTDFKKLYGSDSTAKSLQKIPASL 406
                 ..|.:....|..|:|:.   ||....|..:.:|
Yeast   886 -----LKVGSRETSIPSNLLED---PSQGPAANGRTVR--------------------------- 915

  Fly   407 ASSGMVRHLPDGTKLVNMRQLQARQLKLPSLQRPQDLTALEESHSQNEAAVPSPLPSGHPASG-- 469
               |..:|          :|::|.  |:|...|        :::...:..|...|.||....|
Yeast   916 ---GKFKH----------KQMKAP--KMPDKHR--------DNYYSQKKKVEKALQSGISVKGYN 957

  Fly   470 --SSLRGQVGTVQTIQLRPSLSAGSGQGAVNNGAAPGK 505
              ..||.::.:  |.|:|........:.|.|  |.|.|
Yeast   958 NAPGLRSELKS--TEQIRKDRIIAEKKRAKN--ARPSK 991

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atac3	NP_001246531.1	Ank_4	58..106	CDD:290365	13/67 (19%)
		ANK repeat	58..83	CDD:293786	6/42 (14%)
		ANK	81..204	CDD:238125	28/127 (22%)
		ANK repeat	88..116	CDD:293786	8/29 (28%)
		Ank_2	90..181	CDD:289560	18/95 (19%)
		ANK repeat	118..149	CDD:293786	4/30 (13%)
		ANK repeat	151..181	CDD:293786	6/32 (19%)
		ANK repeat	184..211	CDD:293786	10/26 (38%)
DBP10	NP_010253.2	SrmB	110..649	CDD:223587	9/40 (23%)
		DEADc_DDX54	137..341	CDD:350717
		DBP10CT	820..880	CDD:400455	13/62 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0337
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900