DRSC/TRiP Functional Genomics Resources

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Protein Alignment gol and RNF126

DIOPT Version :10

Sequence 1:NP_001163300.1 Gene:gol / 38006 FlyBaseID:FBgn0004919 Length:601 Species:Drosophila melanogaster
Sequence 2:NP_919442.1 Gene:RNF126 / 55658 HGNCID:21151 Length:311 Species:Homo sapiens


Alignment Length:67 Identity:25/67 - (37%)
Similarity:37/67 - (55%) Gaps:4/67 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   279 KKAIMKIPTKTGKFSDEKDLDSDC-CAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPM 342
            |:.|..:||..   ..|:.:.|.. |.:|.:.|...:.:|.|||.|.||..||.|||.:|.:||:
Human   207 KEKIQALPTVP---VTEEHVGSGLECPVCKDDYALGERVRQLPCNHLFHDGCIVPWLEQHDSCPV 268

  Fly   343 CK 344
            |:
Human   269 CR 270

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
golNP_001163300.1 PA_GRAIL_like 73..217 CDD:239037
HRD1 <237..>347 CDD:227568 25/67 (37%)
RING-H2_RNF130-like 302..347 CDD:438330 19/44 (43%)
RNF126NP_919442.1 Required for interaction with BAG6. /evidence=ECO:0000269|PubMed:24981174 5..100
zinc_ribbon_9 10..40 CDD:433910
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..64
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 94..132
Sufficient for interaction with AICDA. /evidence=ECO:0000269|PubMed:23277564 200..304 25/67 (37%)
RING_Ubox 227..276 CDD:473075 19/44 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 277..311
Blue background indicates that the domain is not in the aligned region.

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