Protein Alignment gol and Rnf133

DIOPT Version :10

• Sequence 1: NP_001163300.1
• Gene: gol / 38006
• FlyBaseID: FBgn0004919
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001423063.1
• Gene: Rnf133 / 386611
• MGIID: 2677436
• Length: 382
• Species: Mus musculus
• Alignment Length: 292
• Identity: 94/292 - (32%)
• Similarity: 146/292 - (50%)
• Gaps: 35/292 - (11%)

  Fly    70 AFLNWSYVEHGNMLCNMEFAQEQARYGEGKVLNVTGRLIHITATDNFSDDYACTP---YIRGTLG 131
            |::|.|:.....||..:   .|...:|...:|.   |:..:..........||.|   :|
Mouse    40 AYMNISFHVGNRMLSEL---GETGVFGRSSILK---RVAGVVVPPEGKIQNACDPNTTFI----- 93

  Fly   132 APIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYN----DKQVMQLEKMQIKGKTRNIAA 192
              :|...|.||||:.||.|.|.:|:|...:..|.||||||    ..||..:.....:.     ..
Mouse    94 --LPRNKEPWIALIERGGCAFTQKIKVASEHGARGVIIYNFPGTGNQVFPMSHQAFED-----IV 151

  Fly   193 VITYQNI-GQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFY 256
            |:...|| |.::...:.||.:||:.:..||:.|..::        ...:||:::...:|.:..||
Mouse   152 VVMIGNIKGMEILHLIRKGVHVTVMVEVGRKHVIWLN--------HYFVSFMIVTTATLAYFTFY 208

  Fly   257 YIQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSDEK-DLDSDCCAICIEAYKPTDTIRILP 320
            :|:|....:.::::.:.|....|||..::..:..|..||: :.::|.|.||.|||||.:.:|||.
Mouse   209 HIRRLWVARIENRRWKRLTRELKKAFGQLQVRVLKEGDEEVNPNADSCVICFEAYKPNEIVRILT 273

  Fly   321 CKHEFHKNCIDPWLIEHRTCPMCKLDVLKFYG 352
            |||.|||||||||::.|.||||||.|:||..|
Mouse   274 CKHFFHKNCIDPWILAHGTCPMCKCDILKALG 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	41/151 (27%)
		HRD1	<237..>347	CDD:227568	45/110 (41%)
		RING-H2_RNF130-like	302..347	CDD:438330	30/44 (68%)
Rnf133	NP_001423063.1	PA_GRAIL_like	43..177	CDD:239037	41/151 (27%)
		HRD1	<183..>297	CDD:227568	44/121 (36%)
		RING-H2_RNF128-like	254..302	CDD:438454	32/47 (68%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..382