DRSC/TRiP Functional Genomics Resources

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Protein Alignment gol and H10E21.5

DIOPT Version :10

Sequence 1:NP_001163300.1 Gene:gol / 38006 FlyBaseID:FBgn0004919 Length:601 Species:Drosophila melanogaster
Sequence 2:NP_497129.1 Gene:H10E21.5 / 175169 WormBaseID:WBGene00019185 Length:473 Species:Caenorhabditis elegans


Alignment Length:348 Identity:119/348 - (34%)
Similarity:161/348 - (46%) Gaps:86/348 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   227 ISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGK 291
            :.|.::|||||||||||:||:|||.||:|||:|||||..|||:..|.|.:..:||:.:|||.|..
 Worm   152 LRSFSKTSVLFVSISFIILMVISLAWLVFYYVQRFRYAHAKDRLQRRLFNAARKALTRIPTMTIT 216

  Fly   292 FSDEKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLKFYGYVFL 356
            ....::|.|| ||:|::.|:..|.||:|||||.:||:||||||:|||||||||.|:||.:||   
 Worm   217 PGMTQELQSD-CAVCLDPYQLQDVIRLLPCKHIYHKSCIDPWLLEHRTCPMCKNDILKHFGY--- 277

  Fly   357 GSEESILEYQPDPPQGLALVEARDESADLNRSRDFVVDFPRVFVLDSGCVVGAREMLFPCRIPER 421
                              ..:.|::......||....||.....|      |.:|...|      
 Worm   278 ------------------WNDIRNDIQMPTNSRGIADDFTIRLEL------GEQEHQAP------ 312

  Fly   422 SQSSLSLRQARDWVSLMSNK-LEEQQGLRSMRNDEMQQQLLSARESARHRRSRSADGRYSTGCFG 485
                     :.|.:|..:|. ..:.||. |..|.|             |..|.|..  |.|    
 Worm   313 ---------SADVISPEANSDTSDSQGF-SFDNSE-------------HHHSESFG--YGT---- 348

  Fly   486 GRQRQPSVLVSSLGQPQLHSEVAQMQRSNSSQALKHLTDAAHAQSRQRQRESFDFARTRRRFMRR 550
                      ||...|||     .:..||:...:..|:....:|..|..|: |..||..|     
 Worm   349 ----------SSTVPPQL-----VLNASNAKSFVMPLSSRGVSQGPQASRD-FRSARAPR----- 392

  Fly   551 ESDEISLRSLPRRGATSAAHRQL 573
             ....||..|||...::|:..|:
 Worm   393 -DHRASLHELPRPQTSAASQGQI 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
golNP_001163300.1 PA_GRAIL_like 73..217 CDD:239037
HRD1 <237..>347 CDD:227568 65/109 (60%)
RING-H2_RNF130-like 302..347 CDD:438330 29/44 (66%)
H10E21.5NP_497129.1 HRD1 <150..325 CDD:227568 87/215 (40%)
RING-H2_RNF130-like 226..271 CDD:438330 30/45 (67%)
Blue background indicates that the domain is not in the aligned region.

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