DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2736 and CG7227

DIOPT Version :9

Sequence 1:	NP_611991.1	Gene:	CG2736 / 37998	FlyBaseID:	FBgn0035090	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001245934.1	Gene:	CG7227 / 34088	FlyBaseID:	FBgn0031970	Length:	518	Species:	Drosophila melanogaster

Alignment Length:	527	Identity:	119/527 - (22%)
Similarity:	200/527 - (37%)	Gaps:	135/527 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 WVKILLCLILACVNVF---------LFVVSWGVDYRILVAREHIRFRQEMPTMDSWINSPFGKLK 61
            |...:|.|:||..::|         .:::.|   :.:|.....|....:.|.||  ||     :.
  Fly     8 WQTSVLGLLLASFSLFSVLYMEQIERWMLEW---FMVLRPGTMISSLWQSPAMD--IN-----VD 62

  Fly    62 NYVFNVTNAEEFRSGRDSRLKVKEIGPIVYRIVGFNDIL--------DRNETNVRYRKHRYRVVE 118
            .|:||.||:|:| |....:.:.:|:||  ||   |.:.:        |.|.| |.||: |.| .:
  Fly    63 LYIFNWTNSEKF-SDPTVKPRFEELGP--YR---FTERMQKVNVEWHDENST-VSYRR-RSR-FD 118

  Fly   119 FLPEESVA----PDVLNWTITSTNNVILGAATKVKHTAPLAAFGFDAALMM--------EDIFVT 171
            |.|:.||.    |      |.:.|.:|:|...|:...:|:.     .:||:        |...:.
  Fly   119 FDPKLSVGRPTDP------IVAPNLLIVGLYQKMVMWSPML-----RSLMLLALNIYGKEQAMIR 172

  Fly   172 DSVYYFLWEFTRPLLQTLSRI-SNIRPNVAVLY---------NALKE---KEEVYTVNIGPKRGI 223
            .:..:....|..|:::....: .::.|.:...|         |...|   ...|||       |.
  Fly   173 PASDWMFDGFDTPMIKMSKMVPPSLVPEMKFPYEKIGYAYPRNGSMEIYGHHNVYT-------GR 230

  Fly   224 ENFFRIETLNGEVI------IREQLPHTRQYDSNSCPFNVSGALDNSLFPPFVQPDTPLSIVAIE 282
            :.|.::    |::.      :.|..|.        |....|....:.:  |.|: ..|:|....:
  Fly   231 DEFQKL----GQIARWRYNNVTEASPR--------CKLKGSAGEFHPI--PLVK-GRPISYFLPD 280

  Fly   283 SCRVLPLTYQRQERYNGLDTFRY-----TLLQSHQKPPG---CLDTSYGVKLPDGMFDVSQCVIN 339
            .||.|.:.|.....:.|:|.|.|     .:......|..   |.|....|:  .|:.::|.|...
  Fly   281 LCRELQVDYSGTTIFEGIDAFVYRGSARNMANGTDNPDNSCYCQDNCQEVR--SGLLNISSCWYG 343

  Fly   340 DAPSAFSMPHFYGSSYNWSQHYEGYTPNAEDHEPYILLEPVTGIPVTEKYRFQSNIPIPDLRRFS 404
             .|...|.|||:.:...:.:..||..|:.:.||..|:|||.||:.:..|.|..:|:.:.......
  Fly   344 -TPVFASYPHFFKADPYYGEQVEGMKPDKDRHEMVIMLEPKTGMVLEIKARIMANLLVEPKTHLI 407

  Fly   405 SRLSRFSNMMIPSFWYEFEMGQLPGFVTSLMWINVNIVQHIQPYCMVLFLVLALWSVLKAIRVAC 469
            .|.:|  ....|..|.::               ||.|...:..|       :.|..:|:.:...|
  Fly   408 YRTAR--RTFFPLIWADY---------------NVRITDDLLVY-------VKLMPILEFVGKIC 448

  Fly   470 GDLGYVV 476
            |.||.|:
  Fly   449 GILGVVL 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2736	NP_611991.1	CD36	10..462	CDD:279474	112/507 (22%)
CG7227	NP_001245934.1	CD36	13..463	CDD:279474	118/522 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450761
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850