DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2736 and Scarb1

DIOPT Version :9

Sequence 1:	NP_611991.1	Gene:	CG2736 / 37998	FlyBaseID:	FBgn0035090	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001192012.1	Gene:	Scarb1 / 20778	MGIID:	893578	Length:	520	Species:	Mus musculus

Alignment Length:	510	Identity:	120/510 - (23%)
Similarity:	213/510 - (41%)	Gaps:	100/510 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QWVKI---LLCLILACVN-VFLFVVSWGVDYRILVAREHIRFRQEMPTMDSW--INSPFGKLKNY 63
            :||.:   .|.|:.|.:. |.:.:|...:..::|   :::|......:...|  |..|| .|..|
Mouse     8 RWVALGLGALGLLFAALGVVMILMVPSLIKQQVL---KNVRIDPSSLSFGMWKEIPVPF-YLSVY 68

  Fly    64 VFNVTNAEEFRSGRDSRLKVKEIGPIVYR------IVGFNDILDRNETNVRYRKHRYRVVEFLPE 122
            .|.|.|..|..:|:  :..|:|.||.|||      .:.|||    |:| |.:.::  |.:.|.|:
Mouse    69 FFEVVNPNEVLNGQ--KPVVRERGPYVYREFRQKVNITFND----NDT-VSFVEN--RSLHFQPD 124

  Fly   123 ES--------VAPDVLNWTITSTNNVILG---------AATKVKHTAPLAAFGFDAALMMEDIFV 170
            :|        |.|::|          :||         .:.|:..|..|...|       :..|:
Mouse   125 KSHGSESDYIVLPNIL----------VLGGSILMESKPVSLKLMMTLALVTMG-------QRAFM 172

  Fly   171 TDSVYYFLWEFTRPLLQTLSR----ISNIRPNVAVLYNALKEKEEVYTVNIGPKRGIENFFRIET 231
            ..:|...||.:..|.:..|:.    :..|:....:..........|:||    ..|::||.||..
Mouse   173 NRTVGEILWGYDDPFVHFLNTYLPDMLPIKGKFGLFVGMNNSNSGVFTV----FTGVQNFSRIHL 233

  Fly   232 L---NGEVIIREQLPHTRQYDSNSCPFNVSGALDNSLFPPFVQPDTPLSIVAIESCRVLPLTYQR 293
            :   ||       |.....:.|..|  |:.......::.||:.|::.|...:.|:||.:.|||..
Mouse   234 VDKWNG-------LSKIDYWHSEQC--NMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYNE 289

  Fly   294 QERYNGLDTFRYTLLQSHQKPPGCLDTSYGVKLPD---------GMFDVSQCVINDAPSAFSMPH 349
            ...:.|:.|:|:|       .|..|..:..|..|:         |:.:||.|... ||...|.||
Mouse   290 SRVFEGIPTYRFT-------APDTLFANGSVYPPNEGFCPCRESGIQNVSTCRFG-APLFLSHPH 346

  Fly   350 FYGSSYNWSQHYEGYTPNAEDHEPYILLEPVTGIPVTEKYRFQSNIPIPDLRRFSSRLSRFSNMM 414
            ||.:....|:...|..||.::|..::.:.||||||:....:.|.::.|..::.. .:..:...::
Mouse   347 FYNADPVLSEAVLGLNPNPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGI-GQTGKIEPVV 410

  Fly   415 IPSFWYEFEMGQLPGFVTSLMWINVNIVQHIQPYCMVLFLVLALWSVLKAIRVAC 469
            :|..|:| :.|.:.|...|..:..:.::..:..|..  :::|.|..:|..:.:.|
Mouse   411 LPLLWFE-QSGAMGGKPLSTFYTQLVLMPQVLHYAQ--YVLLGLGGLLLLVPIIC 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2736	NP_611991.1	CD36	10..462	CDD:279474	116/493 (24%)
Scarb1	NP_001192012.1	CD36	26..447	CDD:279474	111/475 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920