Protein Alignment Tpc2 and CG18418

DIOPT Version :10

• Sequence 1: NP_001246511.1
• Gene: Tpc2 / 37983
• FlyBaseID: FBgn0035078
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_647924.2
• Gene: CG18418 / 38572
• FlyBaseID: FBgn0035568
• Length: 311
• Species: Drosophila melanogaster
• Alignment Length: 319
• Identity: 81/319 - (25%)
• Similarity: 133/319 - (41%)
• Gaps: 44/319 - (13%)

  Fly     3 ENSVVVQLMQAVGGGIAGAATRTITQPLDVLKIRFQMQVEPVTNHKGSK-YRGVIHAFKSVYAEE 66
            |...|...|:.|.||.:|.....|.||||:||.|.|     ::...|:: |:........|...|
  Fly     8 EKKTVPTHMKFVMGGTSGMLATCIVQPLDLLKTRMQ-----ISGTLGTREYKNSFEVLSKVLKNE 67

  Fly    67 GMRGMFRGHNSGQVLSISYALVQFWSYEQLRSMAHQFDYWRER----PFLMFFICGGI-AGCLGA 126
            |:..::.|.::|.:...:|...:...|:.      :.|::|:.    |.::..:..|| ||..||
  Fly    68 GILSLYNGLSAGLLRQATYTSAKMGVYQM------ELDWYRKNFGNYPSMVASMTMGIVAGAFGA 126

  Fly   127 VAAQPFDVVRTQMVAAD---PSSRRSQMNTFTGLRKVYKMEGWMGLSRGLPFTLVQVFPLVGANF 188
            :...|.:|...:|::.:   |..||:..|......::.|.||.:.|.||       ..|.||...
  Fly   127 MCGNPAEVALIRMMSDNRLMPEDRRNYKNVGDAFVRIVKDEGVVALWRG-------CLPTVGRAM 184

  Fly   189 LFYKYLNAAVLMAKPPDQRQEIHGAF-----LFLNGAL-SGVLAKMIVYPADLLKKRIQLMAFKQ 247
            :    :| .|.:|.....:.::||..     |.|..|| ||:|..:...|.|:.|.|||.|
  Fly   185 V----VN-MVQLASYSLMKNQLHGYLSEGIPLHLTAALVSGLLTSVTSMPLDMAKTRIQQM---- 240

  Fly   248 ERKTFGRNPECPTILGCITTTFREEGIGGFYKGMLPTLLKAGLMSAVYFSIYDMFKRHY 306
              |.....||....:..:....:.||....:||..|.|::.|..:...|...:...:.|
  Fly   241 --KVIDGKPEYSGTIDVLKKVLKNEGAFAVWKGFTPYLMRMGPHTIFSFVFLEQMNKAY 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc2	NP_001246511.1	Mito_carr	23..99	CDD:395101	18/76 (24%)
		Mito_carr	108..194	CDD:395101	23/93 (25%)
		Mito_carr	216..307	CDD:395101	25/92 (27%)
CG18418	NP_647924.2	Mito_carr	10..108	CDD:395101	26/108 (24%)
		Mito_carr	109..205	CDD:395101	28/107 (26%)
		Mito_carr	208..300	CDD:395101	26/96 (27%)