Protein Alignment NaCP60E and CATSPER4

DIOPT Version :10

• Sequence 1: NP_001261172.1
• Gene: NaCP60E / 37981
• FlyBaseID: FBgn0085434
• Length: 2896
• Species: Drosophila melanogaster
• Sequence 2: NP_937770.1
• Gene: CATSPER4 / 378807
• HGNCID: 23220
• Length: 472
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 76/287 - (26%)
• Similarity: 120/287 - (41%)
• Gaps: 74/287 - (25%)

  Fly  1751 PAFEWFVLVLIFASSITLCFEDINLDKNKTLKRVLYWINFS-----FCLIFVVEMILKWLALGFS 1810
            |||:..:.:|:..::||     |.|..|..|.:..|.: ||     ...|.:.|::|.||. ||.
Human    92 PAFQLLLALLLVINAIT-----IALRTNSYLDQKHYEL-FSTIDDIVLTILLCEVLLGWLN-GFW 149

  Fly  1811 KYFTSFWTILDFIIVFVSVFSLLIEE------NENLKVLRSLRTLRALRPLRAISRWQGMRIVVN 1869
            .::...|.||:|||||:.:....|.|      |..|:.||.:....|:.||..|         :.
Human   150 IFWKDGWNILNFIIVFILLLRFFINEINIPSINYTLRALRLVHVCMAVEPLARI---------IR 205

  Fly  1870 ALMYAIPSIFNVLLVCLVFWLIFSIMGVQFFGGKFFKCVNEMGELLPITEVNDKWDCIEQNYTWI 1934
            .::.::|.:.|::::.|.|.|:||:.||..||....|
Human   206 VILQSVPDMANIMVLILFFMLVFSVFGVTLFGAFVPK---------------------------- 242

  Fly  1935 NSKITFDHVGMGYLALLQVATFEGWMEVMADAVDARGVDLQPQREANLYAY-----IYFVIFIVC 1994
                .|.::.:....|....|.:||:::.:|.          |.|...||.     |||.|||..
Human   243 ----HFQNIQVALYTLFICITQDGWVDIYSDF----------QTEKREYAMEIGGAIYFTIFITI 293

  Fly  1995 GSFFTLNLFIGVIIDNFNMLKKKYEGG 2021
            |:|..:|||:.|:..|...:.|..|.|
Human   294 GAFIGINLFVIVVTTNLEQMMKAGEQG 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NaCP60E	NP_001261172.1	Ion_trans	125..371	CDD:459842
		Ion_trans	687..902	CDD:459842
		Ion_trans	1751..2019	CDD:459842	74/283 (26%)
		Na_channel_gate	2009..2063	CDD:240441	4/13 (31%)
		Ion_trans	2067..2320	CDD:459842
		GPHH	2332..2378	CDD:465306
CATSPER4	NP_937770.1	Ion_trans	91..313	CDD:459842	73/278 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	416..438