DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16896 and TBC1D23

DIOPT Version :9

Sequence 1:	NP_611973.2	Gene:	CG16896 / 37977	FlyBaseID:	FBgn0035073	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	NP_608569.1	Gene:	TBC1D23 / 33289	FlyBaseID:	FBgn0031304	Length:	689	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	56/262 - (21%)
Similarity:	99/262 - (37%)	Gaps:	51/262 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   501 PEKYRYLIWTSLLDLPCNGPQ---FQELIKLGAPLLVRNRAKKL--KIRNDHQRR--VVIKIWSC 558
            ||..|..:|...||:.....|   |.|:..|.....:|...::.  ::.||.:.:  ||..:.|.
  Fly    33 PEALRPDVWQVCLDVRHKSDQMSLFNEIYDLPFQSQLREDCQRHVDRMGNDEEDKVSVVSDLESI 97

  Fly   559 LAQWCKVLAHADFMP-----HLIFPFVKRMPKNSLVCFELIATLVLNHFQLCFE-FHP---LPPS 614
            :..:|| ..:..:.|     .|:.|         |...:|..:...|.|:...: :.|   .|..
  Fly    98 ITFYCK-NRNLQYEPDNGWIELLLP---------LFALKLNRSDTFNLFESIRDTYIPKGCRPKG 152

  Fly   615 NYLAMCENILQHCDEQLCKFYKSQEMLPKDFAWPLLSTAFSEVLEEEQWLSLWDNIFSEPPWFPV 679
            |...:...:|.:.|.:||....::::.|..::.....:.|:........:::||..|.....|.|
  Fly   153 NVFHVFRLLLLYHDPELCTLLDTKKITPDLYSLTWFQSLFASCSSLSVIIAMWDLYFQNADPFMV 217

  Fly   680 FLVVAYNLIN-REIILRLPDKRSVLFFFHDQNPVDISKLLSKARKLMSKCALALHPQRFMTHFSP 743
            |.:....||| ||.||::          ...:..:|.|.||     :..|||         .|..
  Fly   218 FFLALIILINGREQILQM----------RSSSKEEIIKFLS-----LMPCAL---------EFDD 258

  Fly   744 IP 745
            :|
  Fly   259 VP 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16896	NP_611973.2	WD40	228..>467	CDD:225201
		BAR	766..>952	CDD:299863
		SPFH_like	<817..909	CDD:302763
TBC1D23	NP_608569.1	RabGAP-TBC	34..233	CDD:278964	44/208 (21%)
TBC1D23	NP_608569.1	RHOD	330..429	CDD:197731
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910