Protein Alignment CG16896 and tbc-1

DIOPT Version :9

• Sequence 1: NP_611973.2
• Gene: CG16896 / 37977
• FlyBaseID: FBgn0035073
• Length: 988
• Species: Drosophila melanogaster
• Sequence 2: NP_510485.2
• Gene: tbc-1 / 181592
• WormBaseID: WBGene00008974
• Length: 641
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 106/533 - (19%)
• Similarity: 173/533 - (32%)
• Gaps: 172/533 - (32%)

  Fly   509 WTSLLDL---PCNGPQFQELIKLGAPLLVRNRAKKLK--IRNDHQRRVVIKIWSCLAQWCK---- 564
            |..||.:   |.....:.:|..|.....:||..:||.  ::|   :|.|.::.|.|..:||
 Worm    43 WMRLLGVSMKPNPLDDWDQLYNLNNQCALRNDCRKLANGLKN---KRSVPELESFLTLYCKKRGM 104

  Fly   565 -------------------VLAHADFMPHLIFPF-VKRMPKNS---LVCFELIATLVLNHFQLCF 606
                               |.|..:|  ::.|.| .|.:||::   ...|:|        |:|..
 Worm   105 DYIKDIGWLTILEKILLLNVPAAHEF--NVFFAFTTKYIPKDTRPDAQIFDL--------FRLLL 159

  Fly   607 EFHPLPPSNYLAMCENILQHCDEQLCKFYKSQEMLPKDFAWPLLSTAFSEVLEEEQWLSLWDNIF 671
            ::|....||:|   |::  ||         |..|..|:  |  .:|.||..:..|....||....
 Worm   160 QYHDPQISNHL---ESL--HC---------SPSMYTKN--W--FATLFSSSMSTESCHELWKLYI 206

  Fly   672 SEPPWFPVFLVVAYNLINREIILRLPDKRSVLFFFHDQNPVDISKLLSKARKLMSK-----CALA 731
            .:...|.||.:....|||.        |..:|....|:....:..|.:.|.:|..:     ..||
 Worm   207 EQGDPFLVFHLAIVFLINA--------KDEILQVKRDEKEKAVQILENMAAQLSVEDVPDFFQLA 263

  Fly   732 LH-----PQRFMTHFSPIPKGV----------YPKFLKYPSEWIDEQEYQAVSL---------IK 772
            ||     |:.....|..|..|.          ..|.|..|...||...:..:|.         .:
 Worm   264 LHYSDKTPECIRKDFHYIIFGANFDEEVKEIQMNKMLCLPIPAIDLTSHDEISSGSVNFFIVDTR 328

  Fly   773 HNQEIDAR--IRHLELEEVKIMERLE-------------TGLKQEEHARRL---KEMERVYQD-- 817
            .|.:.|:.  :....|:.|.|::..|             |..:.|:|...|   .:.|..|.:
 Worm   329 SNTDFDSGHFVSSFNLDCVAIVDEPEKFEIALNSLECYKTSRRDEDHYLILGYGSDEEDNYMNML 393

  Fly   818 -----------------------------------TIHREEERITCQRKMLLTYQMEVRRRKSEV 847
                                               .:|.|:....|..:..........:.||.|
 Worm   394 IAMFIQKGKLHVSFVQGGYKKLHDCIGQHNRWELIAMHSEDRCELCSSEKASPKWGFFSKMKSAV 458

  Fly   848 ITKLQESEQRRK-----ILEMEKDMDLLMHSIERERRRHNQEMQLAEDEIRNQEM---------- 897
            .......::|.:     |.|.:|..|....|.:|..:|:.|:.....||..:.||
 Worm   459 SNTSSRMKERVEAVVFPIGEEKKLDDKHADSKQRHGKRYRQQSVFTIDENSDDEMAAGAAVDENP 523

  Fly   898 --ELLAQRYYSDT 908
              |:|..:.:::|
 Worm   524 KEEILLSKEFTET 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16896	NP_611973.2	WD40	228..>467	CDD:225201
		BAR	766..>952	CDD:299863	35/224 (16%)
		SPFH_like	<817..909	CDD:302763	22/146 (15%)
tbc-1	NP_510485.2	RabGAP-TBC	83..230	CDD:295329	43/185 (23%)
		RHOD	321..421	CDD:197731	12/99 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910