DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16896 and AgaP_AGAP007749

DIOPT Version :9

Sequence 1:	NP_611973.2	Gene:	CG16896 / 37977	FlyBaseID:	FBgn0035073	Length:	988	Species:	Drosophila melanogaster
Sequence 2:	XP_317773.4	Gene:	AgaP_AGAP007749 / 1278218	VectorBaseID:	AGAP007749	Length:	717	Species:	Anopheles gambiae

Alignment Length:	257	Identity:	59/257 - (22%)
Similarity:	98/257 - (38%)	Gaps:	49/257 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   501 PEKYRYLIWTSLLDL---PCNGPQFQELIKLGAPLLVRNRAKKL--KIRNDHQRR--VVIKIWSC 558
            ||..|..:|...|.:   |....||.|:..|....|:|:..::.  |:.|:.:.:  ||..:.|.
Mosquito    33 PEALRLDVWQVCLGVRNKPDQLAQFNEIYDLPFQALLRSDCEEFVSKLGNEDEDKVSVVCDLESI 97

  Fly   559 LAQWCK----VLAHADFMPHLIFPF--VKRMPKNSLVCFELIAT-----------LVLNHFQLCF 606
            |..:||    |....:....|:.|.  :|.:..::...||.|..           .|.|.|:|..
Mosquito    98 LTFYCKNRNLVYEPNNGWVELMLPLLSLKLIRSDTYNLFEAIRDTYIPKGCSKNGTVFNVFRLLL 162

  Fly   607 EFHPLPPSNYLAMCENILQHCDEQLCKFYKSQEMLPKDFAWPLLSTAFSEVLEEEQWLSLWDNIF 671
            .:|                  |.:||....::.:.|..:|.....|.|:........||:||..|
Mosquito   163 LYH------------------DPELCTILDTKRITPDCYAMGWFQTLFASTCTLPVVLSMWDLYF 209

  Fly   672 SEPPWFPVFLVVAYNLINR--EIILRLPDKRSVLFFFHDQNPVDISKLLSKARKLMSKCALA 731
            .:...|.||.:....|||:  :|:......:..|..|....|.:|     :|..::..|:||
Mosquito   210 QQSDPFLVFFLSLIVLINQRDQILAMKASTKEELIGFLVNMPCNI-----EADDVLDFCSLA 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16896	NP_611973.2	WD40	228..>467	CDD:225201
		BAR	766..>952	CDD:299863
		SPFH_like	<817..909	CDD:302763
AgaP_AGAP007749	XP_317773.4	RabGAP-TBC	<130..233	CDD:278964	26/120 (22%)
AgaP_AGAP007749	XP_317773.4	RHOD	329..435	CDD:294087
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910