DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Eps-15 and TAX4

DIOPT Version :9

Sequence 1:	NP_611965.2	Gene:	Eps-15 / 37961	FlyBaseID:	FBgn0035060	Length:	1253	Species:	Drosophila melanogaster
Sequence 2:	NP_012452.1	Gene:	TAX4 / 853362	SGDID:	S000003619	Length:	604	Species:	Saccharomyces cerevisiae

Alignment Length:	155	Identity:	41/155 - (26%)
Similarity:	64/155 - (41%)	Gaps:	36/155 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   301 PVMANADWVVTPADLKRFEEIFRQSDLDKDGLVSGLEVKDIFIKSGIPQRSLADIWALCDTNQSG 365
            |.:||.|          .|...:..:|.:|||:..|.||||:.:|.:|:..|..|:.:.||.:.|
Yeast   466 PSLANED----------DESHLQPLNLPQDGLMLNLVVKDIWYRSNLPRDLLVQIYNMVDTRKDG 520

  Fly   366 KLTVEQFALAMWFVE-----RKQRGVDPPHVLNANMVPPSMRATVAGVDLQPQEVKPTYSN---- 421
            .|..:.|.:.||.|:     ||........|.|          :|.|..|....|||..|:
Yeast   521 TLDRKSFIVGMWLVDQCLYGRKLTNELDQRVWN----------SVDGYVLGTINVKPATSDHYHN 575

  Fly   422 -------PELEMISKEIEELARERR 439
                   |....:.:|::.:.|:.|
Yeast   576 ANNPLDKPSKLSVRQELKNIKRDLR 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eps-15	NP_611965.2	EH	16..82	CDD:238009
		EH	126..215	CDD:197477
		EH	137..202	CDD:238009
		EH	307..402	CDD:197477	27/99 (27%)
		EH	318..384	CDD:238009	24/70 (34%)
		RILP-like	<445..548	CDD:304877
		Spc24	529..>584	CDD:285486
TAX4	NP_012452.1	EH	463..557	CDD:197477	31/110 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0998
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900