Protein Alignment Eps-15 and CG9297

DIOPT Version :10

• Sequence 1: NP_611965.2
• Gene: Eps-15 / 37961
• FlyBaseID: FBgn0035060
• Length: 1253
• Species: Drosophila melanogaster
• Sequence 2: NP_788674.1
• Gene: CG9297 / 41688
• FlyBaseID: FBgn0038181
• Length: 952
• Species: Drosophila melanogaster
• Alignment Length: 740
• Identity: 131/740 - (17%)
• Similarity: 208/740 - (28%)
• Gaps: 268/740 - (36%)

  Fly   622 EPDFDEARKTLTKEVQLPKDDPFEENNSGAANQATNGFGSDPFSGQPVNKPAISTGFDDSFN--- 683
            :.|.|...|...::..|..|....|.:.......||....:...|..|....     ||..:
  Fly   244 DEDLDGDGKVNHEDEDLDGDGVKNEKDDDLDGDGTNNSQDEDLDGDGVPNEK-----DDDLDGDG 303

  Fly   684 MSSGFDSGFDAFG--------QSGAGSAFGQTQRDPFGSDAFAANKSNAITPEPGKDDFGSDPFA 740
            :.:..|...|..|        .||..:.......|....:|........:...|.. |..:.|..
  Fly   304 ILNEHDGDVDGDGVPNEHDHKDSGENADDDDDDDDEDDKEAVKKRSKREVDAAPVL-DIEAPPSP 367

  Fly   741 ALHAPTGQGQVLSPNAQKSG-------PPPRPES-----PSPALPPKKSKVPPP----------- 782
            |...|..:..|...:|::..       ..|..|:     |.|.:.|:....|.|
  Fly   368 AEEFPVEEEIVKEASAEEEAEVEAVKEEEPEQEAVQEPEPEPVVEPEAEVQPEPVQQEEEKAESA 432

  Fly   783 ------RPAP------------PRAA--------------QPTGGFGSGGGGGFADFDDFDNKLH 815
                  :|||            |.||              :|.    :.|....|| ||.|.|..
  Fly   433 EAKEEEKPAPVEEAEAEEESVQPEAAPKEPEAVQEEAQEDEPQ----TDGAQDAAD-DDDDTKPE 492

  Fly   816 -------HIPS------------------APSPSAT-----------------ALSPL------- 831
                   |||.                  .....||                 |:.||
  Fly   493 DELLWEGHIPENRRSRQHITELLQLDEEFNAREKATDNVAEIILRDIKRIYENAVKPLETLYKYR 557

  Fly   832 ---------PPTLPAPIPVVSG------SSLLDSFTLFDDPGQIHKQAASTPNPTPITVPTVHTL 881
                     |.....|:.:..|      ||:|:..|          ....|||
  Fly   558 DLSNRHFSDPEIFSKPLILFMGPWSGGKSSILNYLT----------DNEYTPN------------ 600

  Fly   882 LQTSLSTPAAPSPALASLSTSGSGSVAGAGADLPSSVTITTAPSLNNQHLSRSNTPLQNQRTADV 946
               ||.|.|.||||..::...|:.:....|..|.:..|..        .|.:....|: :|...:
  Fly   601 ---SLRTGAEPSPAYFNILMWGNETEVLDGTQLAADYTFA--------GLQKFGQGLE-ERLRGL 653

  Fly   947 KLETKAV--VSVFDAFGEIGTRKAPTPSLITGPTDFKDDPFKDY------RYEDPFSIKDP---- 999
            |:::|.:  |::.:..|.:..||..:          :..||.|.      |.:..|.:.||
  Fly   654 KMKSKILEKVNIVEIPGILEVRKQVS----------RVFPFNDACQWFIDRADIIFLVYDPAKLD 708

  Fly  1000 FAEEGEEELSEGKGADHKRNFAEDFSSGDEIGSAAKTLSNIVNN-NSIKPKAATPLNNDLLQQFD 1063
            ...|.|..|.:.||.:::...                   |:|. :::||:       :||:...
  Fly   709 VGPETEAILDQLKGREYQTRI-------------------ILNKADTVKPE-------ELLRVQG 747

  Fly  1064 AFNLNSSPAPSHHSGTSYHSNSKPSHDSQTALDA---FADFDDFAATLATT--------GGSGAA 1117
            |...|.||..|.......::.|..:|..|....|   .|....|...|.|.        ..|...
  Fly   748 ALIWNISPLMSSAQPPLMYTTSLWTHPYQDGAPARLLLAQERAFLRDLRTAIDKRIEHKIASARR 812

  Fly  1118 TTATTTGNTKLNNSFFDAFND--------------------NFSVIQSSSVPTGVVR---PNDQR 1159
            .......:.|:.:.:.:.||:                    |:.:.:..|..|.:.|   |:.
  Fly   813 FAVRVRNHAKMVDCYLNTFNNHKTLFGNKKRIADDIIDHPQNYHIYEGLSTLTNISRYDLPDP-- 875

  Fly  1160 AKAFDAFNDNFEDQFKTSPNANFAK 1184
                    :.:.|.|:.:|...|.|
  Fly   876 --------EVYRDFFRLNPLYEFKK 892

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eps-15	NP_611965.2	EH	16..82	CDD:238009
		EH	126..215	CDD:197477
		EH	307..402	CDD:197477
		SMC_prok_B	<423..>632	CDD:274008	3/9 (33%)
CG9297	NP_788674.1	MSCRAMM_ClfA	<93..367	CDD:468110	22/128 (17%)
		TSP3 repeat_long	167..205	CDD:275366
		EHD_N	539..570	CDD:465295	4/30 (13%)
		EHD	574..813	CDD:206740	61/308 (20%)