DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3894 and neurl4

DIOPT Version :9

Sequence 1:	NP_611963.5	Gene:	CG3894 / 37959	FlyBaseID:	FBgn0035059	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001090721.1	Gene:	neurl4 / 100036703	XenbaseID:	XB-GENE-5825550	Length:	1477	Species:	Xenopus tropicalis

Alignment Length:	305	Identity:	80/305 - (26%)
Similarity:	124/305 - (40%)	Gaps:	75/305 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 RAAYAAAEQED---PDPDQEQDRGRESPIGSLECAPTLSSRKRQLS--RFHPYHGSNIQLGDDAT 80
            :||.|....|.   |.|..| |.|       |...|........||  |||..||:|..:.:...
Frog   607 QAAQATIMDESDALPLPGDE-DEG-------LALTPGTPCALLSLSDLRFHHLHGANALITNGGR 663

  Fly    81 VAYR---RASFADALTFSERPLAPGDIFLVEIEKIERGWSGHMRLGLTELAPNVIRTSSEGLPHF 142
            ...|   |:.|.||:..|.|||..|::|.:.|:|:...|||.:..|:|.:.|..:.     .|:
Frog   664 TVLRKNSRSEFNDAIVMSSRPLRDGEMFEIVIQKMVDRWSGSIEAGVTAIRPEDLE-----FPN- 722

  Fly   143 ALPDLANLGNSWIYPISKFEMNQRQDANDIIEPETDDAPHRNLLGDATHVRTPRGLLPKRLLRPA 207
            .:.|:..  ::|:...:..    .||.|.:          ||
Frog   723 TMTDIDY--DTWMLSGTAI----MQDGNTL----------RN----------------------- 748

  Fly   208 MGNGNDSDILLTDKGSRIGIIYVPTVQSDSKGELHFIINGVDRGPVSRDIPLNRAPLFVVIDVYG 272
             ..|.|.|.|  ..|||||:  :.|:    :|:||:.|||.|:|.....:|:.| .::.|||:||
Frog   749 -NYGCDLDSL--GAGSRIGM--MKTI----RGDLHYFINGEDQGVACTGLPMGR-DIYAVIDLYG 803

  Fly   273 TTKQIRIIQLEGILSLQSACRNVILESFAEDAISELPLPESIKRF 317
            ...|:.:....|::....:..:|..:|..    |:.|:|....||
Frog   804 QCVQVSLTGGSGLVDNSLSASHVTDKSLP----SQSPVPSVSHRF 844

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3894	NP_611963.5	SPRY_NHR_like	64..280	CDD:293945	59/218 (27%)
CG3894	NP_611963.5	SOCS_SOCS_like	283..321	CDD:239687	8/35 (23%)
neurl4	NP_001090721.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		SPRY_NHR_like	3..165	CDD:293945
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	168..196
		SPRY_NHR_like	253..415	CDD:293945
		SPRY_NHR_like	453..613	CDD:293945	3/5 (60%)
		SPRY_NHR_like	647..811	CDD:293945	59/218 (27%)
		SPRY_NHR_like	843..1008	CDD:293945	2/2 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1012..1041
		SPRY_NHR_like	1050..1209	CDD:293945
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D491552at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920