Protein Alignment CG3894 and neurl4

DIOPT Version :8

• Sequence 1: NP_611963.5
• Gene: CG3894 / 37959
• FlyBaseID: FBgn0035059
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_001090721.1
• Gene: neurl4 / 100036703
• XenbaseID: XB-GENE-5825550
• Length: 1477
• Species: Xenopus tropicalis
• Alignment Length: 305
• Identity: 80/306 (26%)
• Similarity: 124/306 (41%)
• Gaps: 75/306 (25%)

  Fly    21 RAAYAAAEQED---PDPDQEQDRGRESPIGSLECAPTLSSRKRQLS--RFHPYHGSNIQLGDDAT 80
            :||.|....|.   |.|..| |.|       |...|........||  |||..||:|..:.:...
 Frog   607 QAAQATIMDESDALPLPGDE-DEG-------LALTPGTPCALLSLSDLRFHHLHGANALITNGGR 663

  Fly    81 VAYR---RASFADALTFSERPLAPGDIFLVEIEKIERGWSGHMRLGLTELAPNVIRTSSEGLPHF 142
            ...|   |:.|.||:..|.|||..|::|.:.|:|:...|||.:..|:|.:.|..:.     .|:
 Frog   664 TVLRKNSRSEFNDAIVMSSRPLRDGEMFEIVIQKMVDRWSGSIEAGVTAIRPEDLE-----FPN- 722

  Fly   143 ALPDLANLGNSWIYPISKFEMNQRQDANDIIEPETDDAPHRNLLGDATHVRTPRGLLPKRLLRPA 207
            .:.|:..  ::|:...:..    .||.|.:          ||
 Frog   723 TMTDIDY--DTWMLSGTAI----MQDGNTL----------RN----------------------- 748

  Fly   208 MGNGNDSDILLTDKGSRIGIIYVPTVQSDSKGELHFIINGVDRGPVSRDIPLNRAPLFVVIDVYG 272
             ..|.|.|.|  ..|||||:  :.|:    :|:||:.|||.|:|.....:|:.| .::.|||:||
 Frog   749 -NYGCDLDSL--GAGSRIGM--MKTI----RGDLHYFINGEDQGVACTGLPMGR-DIYAVIDLYG 803

  Fly   273 TTKQIRIIQLEGILSLQSACRNVILESFAEDAISELPLPESIKRF 317
            ...|:.:....|::....:..:|..:|..    |:.|:|....||
 Frog   804 QCVQVSLTGGSGLVDNSLSASHVTDKSLP----SQSPVPSVSHRF 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3894	NP_611963.5	SPRY_NHR_like	64..280	CDD:293945	59/219 (27%)
		SOCS_SOCS_like	283..321	CDD:239687	8/36 (22%)
neurl4	NP_001090721.1	SPRY_NHR_like	3..165	CDD:293945
		NEUZ	5..123	CDD:128856
		NEUZ	249..370	CDD:128856
		SPRY_NHR_like	253..415	CDD:293945
		NEUZ	449..572	CDD:128856
		SPRY_NHR_like	453..613	CDD:293945	3/6 (50%)
		NEUZ	645..766	CDD:128856	42/171 (25%)
		SPRY_NHR_like	647..811	CDD:293945	59/219 (27%)
		SPRY_NHR_like	843..1008	CDD:293945	2/3 (67%)
		NEUZ	843..966	CDD:128856	2/3 (67%)
		NEUZ	1049..1164	CDD:128856
		SPRY_NHR_like	1050..1209	CDD:293945

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG4625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D491552at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	3	2.870