DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3894 and neurl1

DIOPT Version :9

Sequence 1:	NP_611963.5	Gene:	CG3894 / 37959	FlyBaseID:	FBgn0035059	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001090706.1	Gene:	neurl1 / 100036686	XenbaseID:	XB-GENE-954449	Length:	555	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	56/238 - (23%)
Similarity:	88/238 - (36%)	Gaps:	75/238 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 GSLECAPTLSSRKRQLSRFHPY-HGSNIQLGDDATVAYRRASFADALTFSERPLAPGDIFLVEIE 110
            |.|...|.|         |||: .||.|.:........|:|||.:|:|||.||:...:...::|.
Frog    39 GGLVITPLL---------FHPHAKGSQIIMDTSQKAVKRQASFCNAITFSNRPVVIHEQVRLKIT 94

  Fly   111 KIERGWSGHMRLGLTELAPNVIRTSSEGLPHFALPDLANLGNSWIYPISKFEMNQRQDANDIIEP 175
            |.:..|||.:|||.|...|:  |.:.:.||.:|.|||.:....|
Frog    95 KKQCCWSGALRLGFTSKDPS--RINPDTLPKYACPDLVSQSGFW--------------------- 136

  Fly   176 ETDDAPHRNLLGDATHVRTPRGLLPKRLLRPAMGNGNDSDILLTDKGSRIGIIYVPTVQSDSKGE 240
                                ...||:..       .|:.:|:         ..:|     |.||.
Frog   137 --------------------AKALPEEF-------ANEGNII---------AFWV-----DKKGR 160

  Fly   241 LHFIINGVDRGPVSRDIPLNRAPLFVVIDVYGTTKQIRIIQLE 283
            :.:.:|..........:.:.. ||:.:|||||.|:.:.::..|
Frog   161 VFYRVNDFGSMLFFSGVRITE-PLWALIDVYGLTRGVELLDSE 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3894	NP_611963.5	SPRY_NHR_like	64..280	CDD:293945	51/216 (24%)
CG3894	NP_611963.5	SOCS_SOCS_like	283..321	CDD:239687	1/1 (100%)
neurl1	NP_001090706.1	NEUZ	44..166	CDD:128856	44/194 (23%)
		Neuralized	277..427	CDD:369249
		mRING-HC-C3HC5_NEU1A	500..543	CDD:319699
		modified RING-HC finger (C3HC5-type)	502..541	CDD:319699
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910