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Protein Alignment Mmp1 and VTN

DIOPT Version :10

Sequence 1:	NP_726473.2	Gene:	Mmp1 / 37949	FlyBaseID:	FBgn0035049	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_000629.3	Gene:	VTN / 7448	HGNCID:	12724	Length:	478	Species:	Homo sapiens

Alignment Length:	451	Identity:	112/451 - (24%)
Similarity:	161/451 - (35%)	Gaps:	178/451 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 GDAF-----------DGQGGTLAHAFFPVFGGDAHFDDAELWTIGSPRGTNLFQVAAHEFGHSLG 231
            ||.|           ||:....|.....| ||.:...|.:..:.|:|..|
Human    65 GDVFTMPEDEYTVYDDGEEKNNATVHEQV-GGPSLTSDLQAQSKGNPEQT--------------- 113

  Fly   232 LSHSDQSSALMAPFYRGFEPVFKLDEDDKAAIQSLYGRKTNQLRPTNVYPATTQRPYSPPKVPLD 296
                               ||.|.:|:..|........:....||..::|..       |:.|.:
Human   114 -------------------PVLKPEEEAPAPEVGASKPEGIDSRPETLHPGR-------PQPPAE 152

  Fly   297 DSICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQLISKGWPGLPGNIDAAFTYKN-- 359
            :.:|.....|...:...|..:||:|...|:|...:|..|||:||...| |:.|.||||||..|
Human   153 EELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVW-GIEGPIDAAFTRINCQ 216

  Fly   360 GKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIPDHLDAAMV-----WGGNGKIYFFKGSKFWR 419
            ||||.|||:||||::...:|..||:.||:||.||||::|||:.     :.|..::|||||.::|.
Human   217 GKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWE 281

  Fly   420 F----DPAK---------------------------------RPPVKASYPKPIS-NWEGVPNNL 446
            :    .|::                                 |.......|:.|| :|.|||..:
Human   282 YQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQV 346

  Fly   447 DAAL---------------------KYTN--GY-------------------------------- 456
            |||:                     ::.|  ||
Human   347 DAAMAGRIYISGMAPRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESN 411

  Fly   457 ------------------------TYFFKGDKYYRFHDARFAVDSATPPFPRPTAHWWFGC 493
                                    .:||.||||||.:.....||:..||:||..|.:|.||
Human   412 LGANNYDDYRMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGC 472

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.