Protein Alignment Mmp1 and Mmp8

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_071557.2
• Gene: Mmp8 / 63849
• RGDID: 631408
• Length: 466
• Species: Rattus norvegicus
• Alignment Length: 461
• Identity: 174/461 - (37%)
• Similarity: 237/461 - (51%)
• Gaps: 73/461 - (15%)

  Fly    33 AEIYLSQFGYLPA----SARNPASSGLHDQRTWVS-AIEEFQSFAGLNITGELDAETMKLMSLPR 92
            ||.||.:|.:||:    ||||         .|.:: .::|.|.|.||..||:.||.|:::|..||
  Rat    36 AENYLRKFYHLPSNQFRSARN---------ATMIAEKLKEMQRFFGLPETGKPDAATIEIMEKPR 91

  Fly    93 CGVRDRVGTGDSRSKRYAL-QGS-RWRVKNLTYKISKYPKRLKRVDVDAEIGRAFAVWSEDTDLT 155
            |||.|   :||     :.| .|| :|...||||:|..:..::.:.:|..||.:||.:||..:.||
  Rat    92 CGVPD---SGD-----FLLTPGSPKWTHTNLTYRIINHTPQMSKAEVKTEIEKAFKIWSVPSTLT 148

  Fly   156 FTRKTSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFP--VFGGDAHFDDAELWTIGSPRGTNL 218
            ||....|...|.|.||..:|||...|||..|.|||||.|  ..|||||||..|.||..| ...||
  Rat   149 FTETLEGEADINIAFVSRDHGDNSPFDGPNGILAHAFQPGRGIGGDAHFDSEETWTQDS-NNYNL 212

  Fly   219 FQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEP-VFKLDEDDKAAIQSLYGRKTNQLRPTNVYPA 282
            |.|||||||||||||||....|||.|.|...|| .:.|.:||...||::||...|.::||.
  Rat   213 FLVAAHEFGHSLGLSHSTDPGALMYPNYAYREPSTYSLPQDDINGIQTIYGPSDNPVQPTG---- 273

  Fly   283 TTQRPYSP----PKVPLDDSICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQL---- 339
                |.:|    |.:..|.:           .:.:||.|.|| |||:       ...:|||
  Rat   274 ----PSTPTACDPHLRFDAA-----------TTLRGEIYFFK-DKYF-------WRRHPQLRTVD 315

  Fly   340 ---ISKGWPGLPGNIDAAF-TYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISE-GFTGIPDHLDA 399
               ||..||.||..:.||: .:.....:.|||.|||......:...||::||. ||......:||
  Rat   316 LNFISLFWPFLPNGLQAAYEDFDRDLVFLFKGRQYWALSAYDLQQGYPRDISNYGFPRSVQAIDA 380

  Fly   400 AMVWGGNGKIYFFKGSKFWRFDPAKRPPVKASYPKPISN-WEGVPNNLDAALKYTNGYTYFFKGD 463
            |:.:  |||.|||..::.||:|..:| .:...||..|:: :.|:...:||..: .:.:..||.|.
  Rat   381 AVSY--NGKTYFFVNNQCWRYDNQRR-SMDPGYPTSIASVFPGINCRIDAVFQ-QDSFFLFFSGP 441

  Fly   464 KYYRFH 469
            :|:.|:
  Rat   442 QYFAFN 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	22/59 (37%)
		Peptidase_M10	115..268	CDD:425668	76/155 (49%)
		HX	298..493	CDD:238046	55/182 (30%)
Mmp8	NP_071557.2	PG_binding_1	32..87	CDD:460223	22/59 (37%)
		Cysteine switch. /evidence=ECO:0000250	90..97		6/9 (67%)
		Peptidase_M10	108..263	CDD:425668	76/155 (49%)
		HX	277..465	CDD:238046	58/194 (30%)
		Hemopexin 1	277..326		18/67 (27%)
		Hemopexin 2	327..373		15/45 (33%)
		Hemopexin 3	375..421		16/48 (33%)
		Hemopexin 4	422..465		7/27 (26%)