Protein Alignment Mmp1 and mmp16b

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_009295076.1
• Gene: mmp16b / 572034
• ZFINID: ZDB-GENE-061009-22
• Length: 618
• Species: Danio rerio
• Alignment Length: 621
• Identity: 204/621 - (32%)
• Similarity: 296/621 - (47%)
• Gaps: 98/621 - (15%)

  Fly     8 VFIVVGTLFSIMAAAQSAPVSTTTQAEIYLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFA 72
            |:.::..|.:.|...:||........|::|.::|||..:..|.|:.  ...:|..|||...|...
Zfish    14 VYALLFWLHNAMWMCRSAAEEHQFSVEVWLQKYGYLHPTPPNMAAQ--RSAQTMHSAIAAMQHKY 76

  Fly    73 GLNITGELDAETMKLMSLPRCGVRD--RVGTGDSRSKRYALQGSRWRVKNLTYKISKYPKRLKRV 135
            ||||||.|:..|:..|..|||||.|  :.|:...|.|||||.|.:|:.::::|.|.....::...
Zfish    77 GLNITGTLNKYTIDWMKKPRCGVPDQLKAGSASRRKKRYALTGQKWQREHISYSIKNVTPKVGNQ 141

  Fly   136 DVDAEIGRAFAVWSEDTDLTFTR-----KTSG--PVHIEIKFVESEHGDGDAFDGQGGTLAHAFF 193
            :....|.|||.||...|.|.|..     ..||  .|.|.|.|....|||...|||:||.||||:|
Zfish   142 ETHDAIRRAFDVWQGVTPLRFEAVPFRDLDSGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYF 206

  Fly   194 --PVFGGDAHFDDAELWTIGSPR-------GTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGF 249
              |..|||.|||..|.||:|:|.       |.:||.||.||.||:|||.||...:|:|||||:..
Zfish   207 PGPGIGGDTHFDSDEPWTLGNPNHDGERTAGNDLFLVAVHELGHALGLEHSSDPTAIMAPFYQYM 271

  Fly   250 E-PVFKLDEDDKAAIQSLYGRKTNQLRPTNVYPATT---------------QRPYSPPKVPLDD- 297
            : ..|||..||...||.:||......:||.:....|               .||:.||:.....
Zfish   272 DTESFKLPHDDLQGIQKIYGPPNKNPQPTRLLTTATPPRLHLPSDPRKHERSRPHRPPQKNKPSH 336

  Fly   298 -----SICKDSKVDTLFNS---AQGETYAFKGDKYYKLTTDSVEEGYPQLISKGWPGLPGNIDAA 354
                 .||     |..||:   .:.|.:.||...::::..:||..|||..||..|.|||..|||.
Zfish   337 PNSKPDIC-----DGGFNTLAILRNELFVFKDQWFWRVRDNSVVPGYPMQISYFWRGLPPKIDAV 396

  Fly   355 FTYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIP-DHLDAAMVWGGNGKIYFFKGSKFW 418
            :....||..||||.::|.::...:...||::||...:|:| ..::.|:.|....|.|||||.::|
Zfish   397 YENSEGKFVFFKGNRFWVFKDTTLQPTYPQDISLFGSGMPTQSIETAVWWEDVAKTYFFKGDRYW 461

  Fly   419 RFDPAKRPPVKASYPKPISNWEGVPNNLDAA-LKYTNGYTYFFKGDKYYRFHDARFAVDSATPPF 482
            |::...| .:...||:||:.|:|:|::...| :...||:|||:||.:|::|::.|..|:   |.:
Zfish   462 RYNEDMR-TMDPGYPQPITVWKGIPDSPQGAFVDKANGFTYFYKGKEYWKFNNQRLRVE---PGY 522

  Fly   483 PRPTAHWWFGCKNTPSSTGNIVEGSDNEFE----QHSMIPHADDGNGDDFDAAVGDHQSNDEPIV 543
            ||.....:.||...|         :|.:::    |....|..||.|.|               ||
Zfish   523 PRSILRDFMGCDGLP---------TDPDWDWSPPQEEEPPQFDDDNVD---------------IV 563

  Fly   544 PEVAERTGNGAMSQSKLTSSSAVSTVITTILMCLVS 579
                          .||.||......:...:.|:::
Zfish   564 --------------LKLESSGGAEKAVAIAIPCVLA 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	20/55 (36%)
		Peptidase_M10	115..268	CDD:425668	70/169 (41%)
		HX	298..493	CDD:238046	68/199 (34%)
mmp16b	XP_009295076.1	PG_binding_1	42..92	CDD:460223	19/51 (37%)
		Peptidase_M10	121..291	CDD:425668	70/169 (41%)
		HX	341..533	CDD:238046	68/200 (34%)
		DUF3377	549..618	CDD:463374	12/66 (18%)