Protein Alignment Mmp1 and mmp17a

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_698601.6
• Gene: mmp17a / 570076
• ZFINID: ZDB-GENE-070820-2
• Length: 597
• Species: Danio rerio
• Alignment Length: 621
• Identity: 196/621 - (31%)
• Similarity: 313/621 - (50%)
• Gaps: 78/621 - (12%)

  Fly     3 NCQSSVFIVVG--TLFSI---MAAAQSAPVSTTTQAEI---YLSQFGYLPASARNPASSGLHDQR 59
            |...:::|:..  .||.:   ::..::||..|..|.::   :||:|||||.|  :|.:..|..:.
Zfish     8 NSARTIWIIYPEMILFPVLWFLSQTRAAPSITAEQMDMGVDWLSKFGYLPPS--DPVNGQLQTKE 70

  Fly    60 TWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDR----VGTGDSRSKRYALQGSRWRVKN 120
            ....||:..|.|.||..||.||..|:.||..|||.:.|.    :..|  |.||.....::|..::
Zfish    71 ALTKAIKAMQRFGGLEETGVLDQATLGLMKTPRCSLPDMSEPDLSAG--RRKRALAPQNKWNKRH 133

  Fly   121 LTYKISKYPKR---LKRVDVDAEIGRAFAVWSEDTDLTFTRKTSGPVHIEIKFVESEHGDGDAFD 182
            |::::..:||.   |.|..|.|.:..|..|||:...|.|.........|:|.|.:::|.||..||
Zfish   134 LSWRVRTFPKESTSLGRDTVRALMYYALKVWSDIAPLNFHEVAGNEADIQIDFTKADHNDGYPFD 198

  Fly   183 GQGGTLAHAFFP---VFGGDAHFDDAELWTIGSP--RGTNLFQVAAHEFGHSLGLSHSDQSSALM 242
            |.|||:||||||   ...||.||||.|.||..:|  .|.:||.||.|||||::||:|:....::|
Zfish   199 GPGGTVAHAFFPGERFTAGDTHFDDDEAWTFRAPDSHGMDLFAVAVHEFGHAIGLAHTSAIESIM 263

  Fly   243 APFYRGFEPV-----FKLDEDDKAAIQSLYGRK---TNQLRPTNVYPATTQRPYSPPKVPLDDSI 299
            .|:|:|  ||     :.|..:||..:..|||.:   ::.|:|.:  |:.|..|.....:|.:.|.
Zfish   264 RPYYQG--PVGDPLKYNLAYEDKVRVWQLYGVRDSVSHTLKPDD--PSQTAEPPVLLDLPENRST 324

  Fly   300 ---CKDS--KVDTLFNSA---QGETYAFKGDKYYKLTTDS-VEEGYPQLISKGWPGLPGNIDAA- 354
               .:|:  :..:.|::.   :||.:.|||..:::||.:. :....|..|.:.|.|||.|:|:.
Zfish   325 IPPARDAPDRCTSHFDAVAQIRGEAFFFKGKYFWRLTREKHLVSLRPAQIHRFWRGLPANLDSVD 389

  Fly   355 FTYK---NGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIP-DHLDAAMVWGGNGKIYFFKGS 415
            ..|:   :.|..||||.:||.::...::..||:.:|:  .|:| :.:||..||..|.|.||||.:
Zfish   390 AVYERPGDHKIVFFKGGKYWVFKDNNVEEGYPRSVSD--FGLPVEGVDAVFVWQHNEKTYFFKDN 452

  Fly   416 KFWRFDPAKRPPVKASYPKPISNWEGVPNNLDAALKYTNGYTYFFKGDKYYRFHDARFAVDSATP 480
            ::||:|...| .:...|||.::.|:|:|..||.|:::::..:|||||.:|:|...:...|:..
Zfish   453 RYWRYDDHLR-RMDLGYPKDMALWKGIPAQLDDAMRWSDSASYFFKGKEYWRVAGSDMEVEVG-- 514

  Fly   481 PFPRPTAHWWFGCKNTPSSTGNIVEGSDNEFEQHSMIPHADDGNGDDFDAAVGDHQSNDEPIVPE 545
             :|||....|..|....|.:..:...|:..........||::|.                    |
Zfish   515 -YPRPIGKDWLVCTEMQSDSPEMQNNSNTRLHGQHHADHAENGY--------------------E 558

  Fly   546 VAERTGNGAMS-QSKLTSSSA-VSTVITTILMCLVS 579
            |...|.:.|.. .::||.|.| |...:.|:.:.|.|
Zfish   559 VCSCTSDSASPLGTRLTLSPAWVFAPLLTLALALSS 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	22/58 (38%)
		Peptidase_M10	115..268	CDD:425668	65/165 (39%)
		HX	298..493	CDD:238046	66/208 (32%)
mmp17a	XP_698601.6	PG_binding_1	49..99	CDD:460223	21/51 (41%)
		ZnMc_MMP	128..292	CDD:239805	65/165 (39%)
		HX	332..526	CDD:238046	64/199 (32%)